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Drug Metabolism & Disposition

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More articles from Special Section on Transporters in Drug Disposition and Pharmacokinetic Prediction

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    Interindividual Differences in the Expression of ATP-Binding Cassette and Solute Carrier Family Transporters in Human Skin: DNA Methylation Regulates Transcriptional Activity of the Human ABCC3 Gene
    Tomoki Takechi, Takeshi Hirota, Tatsuya Sakai, Natsumi Maeda, Daisuke Kobayashi and Ichiro Ieiri
    Drug Metabolism and Disposition May 2018, 46 (5) 628-635; DOI: https://doi.org/10.1124/dmd.117.079061
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    MRP2 Inhibition by HIV Protease Inhibitors in Rat and Human Hepatocytes: A Quantitative Confocal Microscopy Study
    Nico Holmstock, Marlies Oorts, Jan Snoeys and Pieter Annaert
    Drug Metabolism and Disposition May 2018, 46 (5) 697-703; DOI: https://doi.org/10.1124/dmd.117.079467
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    Beyond Competitive Inhibition: Regulation of ABC Transporters by Kinases and Protein-Protein Interactions as Potential Mechanisms of Drug-Drug Interactions
    Rebecca R. Crawford, Praveen K. Potukuchi, Erin G. Schuetz and John D. Schuetz
    Drug Metabolism and Disposition May 2018, 46 (5) 567-580; DOI: https://doi.org/10.1124/dmd.118.080663
  • Open Access
    A Clinical Quantitative Evaluation of Hepatobiliary Transport of [11C]Dehydropravastatin in Humans Using Positron Emission Tomography
    Ken-ichi Kaneko, Masaaki Tanaka, Akira Ishii, Yumiko Katayama, Takayoshi Nakaoka, Satsuki Irie, Hideki Kawahata, Takashi Yamanaga, Yasuhiro Wada, Takeshi Miyake, Kota Toshimoto, Kazuya Maeda, Yilong Cui, Masaru Enomoto, Etsushi Kawamura, Norifumi Kawada, Joji Kawabe, Susumu Shiomi, Hiroyuki Kusuhara, Yuichi Sugiyama and Yasuyoshi Watanabe
    Drug Metabolism and Disposition May 2018, 46 (5) 719-728; DOI: https://doi.org/10.1124/dmd.118.080408
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    Brain Distribution of a Novel MEK Inhibitor E6201: Implications in the Treatment of Melanoma Brain Metastases
    Gautham Gampa, Minjee Kim, Nicholas Cook-Rostie, Janice K. Laramy, Jann N. Sarkaria, Linda Paradiso, Louis DePalatis and William F. Elmquist
    Drug Metabolism and Disposition May 2018, 46 (5) 658-666; DOI: https://doi.org/10.1124/dmd.117.079194
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    Identification of a NFκB Inhibition Site on the Proximal Promoter Region of Human Organic Anion Transporting Polypeptide 1A2 Coding Gene SLCO1A2
    Zhaojian Xiang, Weike Li, Lixue Wang, Jicai Yi, Kaiwen Chen and Mei Hong
    Drug Metabolism and Disposition May 2018, 46 (5) 643-651; DOI: https://doi.org/10.1124/dmd.117.078832
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    Curcumin as an In Vivo Selective Intestinal Breast Cancer Resistance Protein Inhibitor in Cynomolgus Monkeys
    Tsuyoshi Karibe, Tomoki Imaoka, Koji Abe and Osamu Ando
    Drug Metabolism and Disposition May 2018, 46 (5) 667-679; DOI: https://doi.org/10.1124/dmd.117.078931
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    Organic Anion Transporting Polypeptide 1a4 is Responsible for the Hepatic Uptake of Cardiac Glycosides in Mice
    Junichi Takano, Kazuya Maeda, Hiroyuki Kusuhara and Yuichi Sugiyama
    Drug Metabolism and Disposition May 2018, 46 (5) 652-657; DOI: https://doi.org/10.1124/dmd.117.079483
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    Intravital Multiphoton Microscopy with Fluorescent Bile Salts in Rats as an In Vivo Biomarker for Hepatobiliary Transport Inhibition
    Jennifer Ryan, Ryan E. Morgan, Yuan Chen, Laurie P. Volak, Robert T. Dunn and Kenneth W. Dunn
    Drug Metabolism and Disposition May 2018, 46 (5) 704-718; DOI: https://doi.org/10.1124/dmd.117.079277
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    Evaluation of Alteration in Hepatic and Intestinal BCRP Function In Vivo from ABCG2 c.421C>A Polymorphism Based on PBPK Analysis of Rosuvastatin
    Azusa Futatsugi, Kota Toshimoto, Takashi Yoshikado, Yuichi Sugiyama and Yukio Kato
    Drug Metabolism and Disposition May 2018, 46 (5) 749-757; DOI: https://doi.org/10.1124/dmd.117.078816

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