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The multiple depletion curves method provides accurate estimates of CLint, Vmax, and Km: Accuracy and robustness evaluated through experimental data and Monte Carlo simulations

Erik Sjogren, Hans Lennernas, Tommy B. Andersson, Johan Grasjo and Ulf Bredberg
Drug Metabolism and Disposition September 29, 2008, DOI: https://doi.org/10.1124/dmd.108.021477
Erik Sjogren
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Hans Lennernas
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Tommy B. Andersson
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Johan Grasjo
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Ulf Bredberg
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DOI 
https://doi.org/10.1124/dmd.108.021477
PubMed 
18824525

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X

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Drug Metabolism and Disposition: 49 (3)
Drug Metabolism and Disposition
Vol. 49, Issue 3
1 Mar 2021
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The multiple depletion curves method provides accurate estimates of CLint, Vmax, and Km: Accuracy and robustness evaluated through experimental data and Monte Carlo simulations

Erik Sjogren, Hans Lennernas, Tommy B. Andersson, Johan Grasjo and Ulf Bredberg
Drug Metabolism and Disposition September 29, 2008, DOI: https://doi.org/10.1124/dmd.108.021477

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OtherArticle

The multiple depletion curves method provides accurate estimates of CLint, Vmax, and Km: Accuracy and robustness evaluated through experimental data and Monte Carlo simulations

Erik Sjogren, Hans Lennernas, Tommy B. Andersson, Johan Grasjo and Ulf Bredberg
Drug Metabolism and Disposition September 29, 2008, DOI: https://doi.org/10.1124/dmd.108.021477
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