Limited brain distribution of Ro 64-0802, a pharmacologically active form of oseltamivir, by active efflux across the blood–brain barrier mediated by organic anion transporter 3 (Oat3/Slc22a8) and multidrug resistance-associated protein 4 (Mrp4/Abcc4)

Atsushi Ose; Mototsugu Ito; Hiroyuki Kusuhara; Kenzo Yamatsugu; Motomu Kanai,; Masakatsu Shibasaki; Masakiyo Hosokawa; John D. Schuetz; Yuichi Sugiyama

doi:10.1124/dmd.108.024018

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Limited brain distribution of Ro 64-0802, a pharmacologically active form of oseltamivir, by active efflux across the blood–brain barrier mediated by organic anion transporter 3 (Oat3/Slc22a8) and multidrug resistance-associated protein 4 (Mrp4/Abcc4)

Atsushi Ose, Mototsugu Ito, Hiroyuki Kusuhara, Kenzo Yamatsugu, Motomu Kanai,, Masakatsu Shibasaki, Masakiyo Hosokawa, John D. Schuetz and Yuichi Sugiyama

Drug Metabolism and Disposition November 24, 2008, DOI: https://doi.org/10.1124/dmd.108.024018

Atsushi Ose

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Mototsugu Ito

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Hiroyuki Kusuhara

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Kenzo Yamatsugu

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Motomu Kanai,

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Masakatsu Shibasaki

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Masakiyo Hosokawa

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John D. Schuetz

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Yuichi Sugiyama

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Limited brain distribution of Ro 64-0802, a pharmacologically active form of oseltamivir, by active efflux across the blood–brain barrier mediated by organic anion transporter 3 (Oat3/Slc22a8) and multidrug resistance-associated protein 4 (Mrp4/Abcc4)

Atsushi Ose, Mototsugu Ito, Hiroyuki Kusuhara, Kenzo Yamatsugu, Motomu Kanai,, Masakatsu Shibasaki, Masakiyo Hosokawa, John D. Schuetz and Yuichi Sugiyama

Drug Metabolism and Disposition November 24, 2008, DOI: https://doi.org/10.1124/dmd.108.024018

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Limited brain distribution of Ro 64-0802, a pharmacologically active form of oseltamivir, by active efflux across the blood–brain barrier mediated by organic anion transporter 3 (Oat3/Slc22a8) and multidrug resistance-associated protein 4 (Mrp4/Abcc4)

Atsushi Ose, Mototsugu Ito, Hiroyuki Kusuhara, Kenzo Yamatsugu, Motomu Kanai,, Masakatsu Shibasaki, Masakiyo Hosokawa, John D. Schuetz and Yuichi Sugiyama

Drug Metabolism and Disposition November 24, 2008, DOI: https://doi.org/10.1124/dmd.108.024018

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