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Research ArticleArticle

An Evaluation of the Dilution Method for Identifying Metabolism-dependent Inhibitors (MDIs) of Cytochrome P450 (CYP) Enzymes

Andrew Parkinson, Faraz Kazmi, David B. Buckley, Phyllis Yerino, Brandy L. Paris, Jeff Holsapple, Paul Toren, Steve M. Otradovec and Brian W. Ogilvie
Drug Metabolism and Disposition April 27, 2011, dmd.111.038596; DOI: https://doi.org/10.1124/dmd.111.038596
Andrew Parkinson
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  • For correspondence: aparkinson@xenotechllc.com
Faraz Kazmi
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David B. Buckley
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Phyllis Yerino
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Brandy L. Paris
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Jeff Holsapple
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Paul Toren
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Steve M. Otradovec
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Article Information

dmd.111.038596
DOI 
https://doi.org/10.1124/dmd.111.038596
PubMed 
21525169

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received February 8, 2011
  • Accepted April 27, 2011
  • Published online April 27, 2011.

Article Versions

  • You are currently viewing an Earlier version of this article (April 27, 2011 - 07:45).
  • View the most recent version of this article
Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Andrew Parkinson1,
  2. Faraz Kazmi,
  3. David B. Buckley,
  4. Phyllis Yerino,
  5. Brandy L. Paris,
  6. Jeff Holsapple,
  7. Paul Toren,
  8. Steve M. Otradovec and
  9. Brian W. Ogilvie
  1. XenoTech, LLC
  1. ↵1 E-mail: aparkinson{at}xenotechllc.com

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Drug Metabolism and Disposition: 50 (8)
Drug Metabolism and Disposition
Vol. 50, Issue 8
1 Aug 2022
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Research ArticleArticle

An Evaluation of the Dilution Method for Identifying Metabolism-dependent Inhibitors (MDIs) of Cytochrome P450 (CYP) Enzymes

Andrew Parkinson, Faraz Kazmi, David B. Buckley, Phyllis Yerino, Brandy L. Paris, Jeff Holsapple, Paul Toren, Steve M. Otradovec and Brian W. Ogilvie
Drug Metabolism and Disposition April 27, 2011, dmd.111.038596; DOI: https://doi.org/10.1124/dmd.111.038596

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Research ArticleArticle

An Evaluation of the Dilution Method for Identifying Metabolism-dependent Inhibitors (MDIs) of Cytochrome P450 (CYP) Enzymes

Andrew Parkinson, Faraz Kazmi, David B. Buckley, Phyllis Yerino, Brandy L. Paris, Jeff Holsapple, Paul Toren, Steve M. Otradovec and Brian W. Ogilvie
Drug Metabolism and Disposition April 27, 2011, dmd.111.038596; DOI: https://doi.org/10.1124/dmd.111.038596
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