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Prediction of Crizotinib-Midazolam Interaction Using the Simcyp Population-Based Simulator: Comparison of CYP3A Time-Dependent Inhibition Between Human Liver Microsomes Versus Hepatocytes

Jialin Mao, Theodore R Johnson, Zhongzhou Shen and Shinji Yamazaki
Drug Metabolism and Disposition November 5, 2012, dmd.112.049114; DOI: https://doi.org/10.1124/dmd.112.049114
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Research ArticleArticle

Prediction of Crizotinib-Midazolam Interaction Using the Simcyp Population-Based Simulator: Comparison of CYP3A Time-Dependent Inhibition Between Human Liver Microsomes Versus Hepatocytes

Jialin Mao, Theodore R Johnson, Zhongzhou Shen and Shinji Yamazaki
Drug Metabolism and Disposition November 5, 2012, dmd.112.049114; DOI: https://doi.org/10.1124/dmd.112.049114
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