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Research ArticleArticle

Metabolism and Pharmacokinetics of 3-n-Butylphthalide (NBP) in Humans: The Role of Cytochrome P450s and Alcohol Dehydrogenase in Biotransformation

Xingxing Diao, Pan Deng, Cen Xie, Xiuli Li, Dafang Zhong, Yifan Zhang and Xiaoyan Chen
Drug Metabolism and Disposition November 20, 2012, dmd.112.049684; DOI: https://doi.org/10.1124/dmd.112.049684

Article Information

dmd.112.049684
DOI 
https://doi.org/10.1124/dmd.112.049684
PubMed 
23169608
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received October 17, 2012
  • Accepted November 20, 2012
  • Published online November 20, 2012.

Article Versions

Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Xingxing Diao,
  2. Pan Deng,
  3. Cen Xie,
  4. Xiuli Li,
  5. Dafang Zhong,
  6. Yifan Zhang, and
  7. Xiaoyan Chen1
  1. Shanghai Institute of Materia Medica, Chinese Academy of Sciences
  1. ↵1 E-mail: xychen{at}mail.shcnc.ac.cn

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Research ArticleArticle

Metabolism and Pharmacokinetics of 3-n-Butylphthalide (NBP) in Humans: The Role of Cytochrome P450s and Alcohol Dehydrogenase in Biotransformation

Xingxing Diao, Pan Deng, Cen Xie, Xiuli Li, Dafang Zhong, Yifan Zhang and Xiaoyan Chen
Drug Metabolism and Disposition November 20, 2012, dmd.112.049684; DOI: https://doi.org/10.1124/dmd.112.049684
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