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Research ArticleArticle

The Effect of Ritonavir on Human CYP2B6 Catalytic Activity: Heme Modification Contributes to the Mechanism-Based Inactivation of CYP2B6 and CYP3A4 by Ritonavir

Hsia-lien Lin, Jaime D'Agostino, Cesar Kenaan, Diane Calinski and Paul F Hollenberg
Drug Metabolism and Disposition July 25, 2013, dmd.113.053108; DOI: https://doi.org/10.1124/dmd.113.053108

Article Information

dmd.113.053108
DOI 
https://doi.org/10.1124/dmd.113.053108
PubMed 
23886699
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Published online July 25, 2013.

Article Versions

Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Hsia-lien Lin,
  2. Jaime D'Agostino,
  3. Cesar Kenaan,
  4. Diane Calinski, and
  5. Paul F Hollenberg1
  1. University of Michigan
  1. ↵1 E-mail: phollen{at}umich.edu

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Research ArticleArticle

The Effect of Ritonavir on Human CYP2B6 Catalytic Activity: Heme Modification Contributes to the Mechanism-Based Inactivation of CYP2B6 and CYP3A4 by Ritonavir

Hsia-lien Lin, Jaime D'Agostino, Cesar Kenaan, Diane Calinski and Paul F Hollenberg
Drug Metabolism and Disposition July 25, 2013, dmd.113.053108; DOI: https://doi.org/10.1124/dmd.113.053108
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