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Research ArticleArticle

An Automated High-Throughput Metabolic Stability Assay Using an Integrated High-Resolution Accurate Mass Method and Automated Data Analysis Software

Pranav Shah, R. Scott Obach, Dac-Trung Nguyen, Edward Kerns, Amy Q Wang, Alexey Zakharov, Anton Simeonov, Cornelis E.C.A Hop, John McKew and Xin Xu
Drug Metabolism and Disposition July 22, 2016, dmd.116.072017; DOI: https://doi.org/10.1124/dmd.116.072017

Article Information

dmd.116.072017
DOI 
https://doi.org/10.1124/dmd.116.072017
PubMed 
27417180
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Published online July 22, 2016.

Article Versions

Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Pranav Shah1,
  2. R. Scott Obach2,
  3. Dac-Trung Nguyen1,
  4. Edward Kerns3,
  5. Amy Q Wang1,
  6. Alexey Zakharov1,
  7. Anton Simeonov1,
  8. Cornelis E.C.A Hop4,
  9. John McKew5, and
  10. Xin Xu1,6
  1. 1 NCATS;
  2. 2 Pfizer Global Research and Development;
  3. 3 Discovery ADME;
  4. 4 Genentech;
  5. 5 Lumos Pharma
  1. ↵*Address correspondence to: xin.xu3{at}nih.gov

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Research ArticleArticle

An Automated High-Throughput Metabolic Stability Assay Using an Integrated High-Resolution Accurate Mass Method and Automated Data Analysis Software

Pranav Shah, R. Scott Obach, Dac-Trung Nguyen, Edward Kerns, Amy Q Wang, Alexey Zakharov, Anton Simeonov, Cornelis E.C.A Hop, John McKew and Xin Xu
Drug Metabolism and Disposition July 22, 2016, dmd.116.072017; DOI: https://doi.org/10.1124/dmd.116.072017
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