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In Vitro and in Vivo Drug-Drug Interaction Studies to Assess the Effect of Abiraterone Acetate, Abiraterone, and Metabolites of Abiraterone on CYP2C8 Activity

Johan Monbaliu, Martha Gonzalez, Apexa Bernard, James Jiao, Carlo Sensenhauser, Jan Snoeys, Hans Stieltjes, Inneke Wynant, Johan W Smit and Caly Chien
Drug Metabolism and Disposition August 8, 2016, dmd.116.070672; DOI: https://doi.org/10.1124/dmd.116.070672

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      Supplemental Figure 1 - Chemical structures of abiraterone acetate, abiraterone, and the main metabolites in humans in the proposed main biotransformation pathway...

      Supplemental Figure 2 - Chemical structures of pioglitazone, M-IV, and M-III...
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Research ArticleArticle

In Vitro and in Vivo Drug-Drug Interaction Studies to Assess the Effect of Abiraterone Acetate, Abiraterone, and Metabolites of Abiraterone on CYP2C8 Activity

Johan Monbaliu, Martha Gonzalez, Apexa Bernard, James Jiao, Carlo Sensenhauser, Jan Snoeys, Hans Stieltjes, Inneke Wynant, Johan W Smit and Caly Chien
Drug Metabolism and Disposition August 8, 2016, dmd.116.070672; DOI: https://doi.org/10.1124/dmd.116.070672
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