Data Supplement

• Supplemental Data -

  Supplementary Table 1 - Abundance of CYP enzymes and accessory proteins (P450 oxidoreductase, POR; cytochrome b5A, CYB5A) in a bank of liver microsomes (N =59) representing 4 different breeds and mixed-breed dogs measured by LC-MS/MS.

  Supplementary Figure 1 - Dog breed-associated variability in liver microsomal protein abundance (in pmoles / mg) of CYP1A1 (A), CYP1A2 (B), CYP2A13 (C), CYP2A25 (D), CYP2B11 (E), CYP2C21 (F), CYP2C41 (G), CYP2D15 (H), CYP2E1 (I), CYP3A12 (J), CYP3A26 (K), POR (L), and CYB5A (M).