Article Figures & Data
Additional Files
Data Supplement
- Supplemental Data -
Supplementary Table 1 - MLEM population parameters for simultaneous fit of IV and ICV hA40 data with Models II, IIA and IIB by ADAPT5®.
Supplementary Table 2 - MLEM population parameters for simultaneous fit of IV and ICV hA40 data with Model III, IIIA and IIIB by ADAPT5®.
Supplementary Figure 1 - Prediction plots for Model II (upper panel), Model IIA (middle panel, setting and V1,plasma and V6,CSF constant as those for Model II) and Model IIB (bottom panel, setting and V1,plasma V6,CSF and k61 constant as those for Model II) after IV and ICV injections.
Supplementary Figure 2 - Prediction plots for Model III (upper panel), Model IIIA (middle panel, setting and V1,plasma and V8,CSF constant as those for Model III) and Model IIIB (bottom panel, setting and V1,plasma V8,CSF and k81 constant as those for Model III) after IV and ICV injections.
- Supplemental Data -