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Dual action of acidic microenvironment on the enrichment of the active metabolite of disulfiram in tumor tissues

Chongzhuang Tang, Xiaoyan Pang, Zitao Guo, Runcong Guo, Lu Liu and Xiaoyan Chen
Drug Metabolism and Disposition March 24, 2021, DMD-AR-2020-000317; DOI: https://doi.org/10.1124/dmd.120.000317

Article Information

DMD-AR-2020-000317
DOI 
https://doi.org/10.1124/dmd.120.000317
PubMed 
33762296
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Published online March 24, 2021.
Copyright & Usage 
Copyright © 2020 American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Chongzhuang Tang1,
  2. Xiaoyan Pang1,
  3. Zitao Guo1,
  4. Runcong Guo1,
  5. Lu Liu1, and
  6. Xiaoyan Chen1,*
  1. 1Shanghai Institute of Materia Medica, China
  1. ↵* Corresponding Author:
    Xiaoyan Chen, Shanghai Institute of Materia Medica, 501 haike Road, Zhangjiang Hi-Tech. Park, Shanghai, 201210, China. E-mail: xychen{at}simm.ac.cn

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Acidic microenvironment enhances tumor distribution of CuET

Chongzhuang Tang, Xiaoyan Pang, Zitao Guo, Runcong Guo, Lu Liu and Xiaoyan Chen
Drug Metabolism and Disposition March 24, 2021, DMD-AR-2020-000317; DOI: https://doi.org/10.1124/dmd.120.000317
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