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Static and Dynamic Projections of Drug-Drug Interactions Caused by Cytochrome P450 3A Time-Dependent Inhibitors Measured in Human Liver Microsomes and Hepatocytes
Elaine Tseng, Heather Eng, Jian Lin, Matthew A. Cerny, David A. Tess, Theunis C. Goosen and R. Scott Obach
Drug Metabolism and Disposition July 29, 2021, DMD-AR-2021-000497; DOI: https://doi.org/10.1124/dmd.121.000497
Elaine Tseng
1Pharmacokinetics, Dynamics, and Metabolism, Pfizer Global Research and Development, United States
Heather Eng
1Pharmacokinetics, Dynamics, and Metabolism, Pfizer Global Research and Development, United States
Jian Lin
2PDM, Pfizer Inc, United States
Matthew A. Cerny
3PDM, Pfizer Global Research and Development, United States
David A. Tess
4Medicine Design, Pfizer Inc., United States
Theunis C. Goosen
5Pharmacokinetics, Dynamics & Metabolism, Pfizer, Inc, United States
R. Scott Obach
6Groton Laboratories, Pfizer Global Research and Development, United States
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Drug Interactions for CYP3A Time-Dependent Inhibitors.
Elaine Tseng, Heather Eng, Jian Lin, Matthew A. Cerny, David A. Tess, Theunis C. Goosen and R. Scott Obach
Drug Metabolism and Disposition July 29, 2021, DMD-AR-2021-000497; DOI: https://doi.org/10.1124/dmd.121.000497
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