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Infigratinib is a Reversible Inhibitor and Mechanism-based Inactivator of Cytochrome P450 3A4
Lloyd Wei Tat Tang, Jian Wei Teng, Siew Kwan Koh, Lei Zhou, Mei Lin Go, Eric Chun Yong Chan, Ravi Kumar Verma and Hao Fan
Drug Metabolism and Disposition July 29, 2021, DMD-AR-2021-000508; DOI: https://doi.org/10.1124/dmd.121.000508
Lloyd Wei Tat Tang
1Pharmacy, National University of Singapore, Singapore
Jian Wei Teng
2National University of Singapore, Singapore
Siew Kwan Koh
3Singapore Eye Research Institute, Singapore
Lei Zhou
3Singapore Eye Research Institute, Singapore
Mei Lin Go
2National University of Singapore, Singapore
Eric Chun Yong Chan
1Pharmacy, National University of Singapore, Singapore
Ravi Kumar Verma
4Bioinformatics Institute (BII), Agency for Science, Technology and Research (A*STAR), Singapore
Hao Fan
4Bioinformatics Institute (BII), Agency for Science, Technology and Research (A*STAR), Singapore
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Inhibition and Inactivation of CYP3A4 by Infigratinib
Lloyd Wei Tat Tang, Jian Wei Teng, Siew Kwan Koh, Lei Zhou, Mei Lin Go, Eric Chun Yong Chan, Ravi Kumar Verma and Hao Fan
Drug Metabolism and Disposition July 29, 2021, DMD-AR-2021-000508; DOI: https://doi.org/10.1124/dmd.121.000508
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