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­­­­­­Cannabinoid metabolites as inhibitors of major hepatic CYP450 enzymes, with implications for cannabis-drug interactions

Shamema Nasrin, Christy J.W. Watson, Yadira X Perez-Paramo and Philip Lazarus
Drug Metabolism and Disposition September 7, 2021, DMD-AR-2021-000442; DOI: https://doi.org/10.1124/dmd.121.000442

Article Information

DMD-AR-2021-000442
DOI 
https://doi.org/10.1124/dmd.121.000442
PubMed 
34493602
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Published online September 7, 2021.

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Copyright & Usage 
© 2020 The Authors. This is an open access article under the terms of the Creative Commons Attribution Non-Commercial License, which permits use, distribution, and reproduction in any medium, provided that the original work is properly cited and is not used for commercial purposes.

Author Information

  1. Shamema Nasrin1,
  2. Christy J.W. Watson2,
  3. Yadira X Perez-Paramo3, and
  4. Philip Lazarus4,*
  1. 1Washington state university, United States
  2. 2Pharmaceutical Sciences, Washington State University, United States
  3. 3OMNI-Biomarker Development, Genentech Inc., United States
  4. 4Pharmaceutical Sciences, Washington State University College of Pharmacy, United States
  1. ↵* Corresponding Author:
    Philip Lazarus, Pharmaceutical Sciences, Washington State University College of Pharmacy, Riverpoint Drive, Spokane, 99212, United States. E-mail: phil.lazarus{at}wsu.edu

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Cannabinoid metabolites as CYP450 inhibitors

Shamema Nasrin, Christy J.W. Watson, Yadira X Perez-Paramo and Philip Lazarus
Drug Metabolism and Disposition September 7, 2021, DMD-AR-2021-000442; DOI: https://doi.org/10.1124/dmd.121.000442
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