Data Supplement

• Supplemental Data -

  Supplemental Figure 1. Relative quantification of V5-tagged CYP450-overexpressed enzymes in HEK293 cells by Western blot analysis

  Supplemental Figure 2. Other genotype-phenotype correlations

  Supplemental Table 1. Reported IC50 values of CYP inhibitors.

  Supplemental Table 2. UHPLC-MS/MS performance parameters

  Supplemental Table 3. Allelic frequencies and functional effects of major SNPs in CYP2A6, CYP2C19 and CYP2B6.