Data Supplement

• Supplemental Data -

  Supplemental Table 1. Demographic and clinical details of the donors of the 27 liver samples.

   Supplemental Table 2. Agreement in identification between technical replicates. 

  Supplemental Table 3. Similarity matrix between biological samples based on percent identical peptide (PIP).

  Supplemental Table 4. Abundance (in pmol mg^-1) of cytochrome P450 enzymes, UGT enzymes, ABC transporters, and solute carriers using HiN with BSA as a standard.

  Supplemental Table 5. Abundance (in pmol mg^-1) of cytochrome P450 enzymes, UGT enzymes, ABC transporters, and solute carriers using iBAQ with BSA as a standard.

  Supplemental Table 6. Abundance (in pmol mg^-1) of cytochrome P450 enzymes, UGT enzymes, ABC transporters, and solute carriers using the TPA method.

  Supplemental Table 7. Effect of age, body mass index (BMI) and genotype on the abundance of enzymes and transporters measured using HiN, iBAQ and TPA label-free methods.

  Supplemental Figure 1. Relative abundance of (A) CYPs, (B) UGTs and (C) ABC transporters in human liver determined using either HiN, iBAQ or TPA.