Article Figures & Data
Additional Files
Data Supplement
- Supplemental Figures -
Supplemental Figure S1: Time- and ATP-dependent uptake of [3H]NMQ (0.1M) in MDR1 and control vesicles.
Supplemental Figure S2-1: P-gp IC50 curves of the test compounds measured in bidirectional transport net secretory flux (NSF), efflux ratio (ER) and vesicular (V) inhibition assays
Supplemental Figure S2-2: P-gp IC50 curves of the test compounds measured in bidirectional transport net secretory flux (NSF), efflux ratio (ER) and vesicular (V) inhibition assays
- Supplemental Tables -
Supplemental Table 1. LC/MS/MS Parameters
Supplemental Table 2: Clinical DDI data of test set compounds with orally administered digoxin
Supplemental Table 3: In vitro P-gp IC50 variability for verapamil and quinidine measured in MDR1 vesicles and bidirectional transport (BDT) inhibition assays
- Supplemental Figures -