OtherCommentary
Examining Physiologically-Based Pharmacokinetic (PBPK) Model Assumptions for Cross-Tissue Similarity of Kcat: The Case Example of Uridine 5'-diphosphate Glucuronosyltransferase (UGT)
Anika N Ahmed, Amin Rostami-Hodjegan, Jill Barber and Zubida M. Al-Majdoub
Drug Metabolism and Disposition May 30, 2022, DMD-COM-2021-000813; DOI: https://doi.org/10.1124/dmd.121.000813
Anika N Ahmed
1Centre for Applied Pharmacokinetic Research,, The University of Manchester, United Kingdom
Amin Rostami-Hodjegan
2Systems Pharmacology, Manchester Pharmacy School, University of Manchester, United Kingdom
Jill Barber
3Pharmacy and Pharmaceutical Sciences, University of Manchester, United Kingdom
Zubida M. Al-Majdoub
4Division of Pharmacy and Optometry, University of Manchester, United Kingdom
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OtherCommentary
Kcat assessment of UGT enzymes across different organs.
Anika N Ahmed, Amin Rostami-Hodjegan, Jill Barber and Zubida M. Al-Majdoub
Drug Metabolism and Disposition May 30, 2022, DMD-COM-2021-000813; DOI: https://doi.org/10.1124/dmd.121.000813
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