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Drug Metabolism & Disposition

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Repression of OATP1B Expression and Increase of Plasma Coproporphyrin Level as Evidence for OATP1B Down-regulation in Cynomolgus Monkeys Treated with Chenodeoxycholic Acid

Yueping Zhang, Shen-Jue Chen, Cliff Chen, Xue-Qing Chen, Sagnik Chatterjee, David J. Shuster, Heather Dexter, Laura Armstrong, Elizabeth M. Joshi, Zheng Yang and Hong Shen
Drug Metabolism and Disposition May 30, 2022, DMD-AR-2022-000875; DOI: https://doi.org/10.1124/dmd.122.000875
Yueping Zhang
1Bristol-Myers Squibb, United States
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Shen-Jue Chen
2Bristol Myers Squibb, United States
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Cliff Chen
2Bristol Myers Squibb, United States
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Xue-Qing Chen
2Bristol Myers Squibb, United States
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Sagnik Chatterjee
3Bristol Myers Squib, India
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David J. Shuster
2Bristol Myers Squibb, United States
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Heather Dexter
2Bristol Myers Squibb, United States
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Laura Armstrong
2Bristol Myers Squibb, United States
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Elizabeth M. Joshi
2Bristol Myers Squibb, United States
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Zheng Yang
2Bristol Myers Squibb, United States
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  • ORCID record for Zheng Yang
Hong Shen
4Drug Metabolism and Pharmacokinetics, Bristol Myers Squibb, United States
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  • For correspondence: Hong.Shen1@bms.com
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Drug Metabolism and Disposition: 50 (6)
Drug Metabolism and Disposition
Vol. 50, Issue 6
1 Jun 2022
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OtherArticle

OATP1B down-regulation in CDCA treated monkeys

Yueping Zhang, Shen-Jue Chen, Cliff Chen, Xue-Qing Chen, Sagnik Chatterjee, David J. Shuster, Heather Dexter, Laura Armstrong, Elizabeth M. Joshi, Zheng Yang and Hong Shen
Drug Metabolism and Disposition May 30, 2022, DMD-AR-2022-000875; DOI: https://doi.org/10.1124/dmd.122.000875

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OtherArticle

OATP1B down-regulation in CDCA treated monkeys

Yueping Zhang, Shen-Jue Chen, Cliff Chen, Xue-Qing Chen, Sagnik Chatterjee, David J. Shuster, Heather Dexter, Laura Armstrong, Elizabeth M. Joshi, Zheng Yang and Hong Shen
Drug Metabolism and Disposition May 30, 2022, DMD-AR-2022-000875; DOI: https://doi.org/10.1124/dmd.122.000875
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