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Repression of OATP1B Expression and Increase of Plasma Coproporphyrin Level as Evidence for OATP1B Down-regulation in Cynomolgus Monkeys Treated with Chenodeoxycholic Acid
Yueping Zhang, Shen-Jue Chen, Cliff Chen, Xue-Qing Chen, Sagnik Chatterjee, David J. Shuster, Heather Dexter, Laura Armstrong, Elizabeth M. Joshi, Zheng Yang and Hong Shen
Drug Metabolism and Disposition May 30, 2022, DMD-AR-2022-000875; DOI: https://doi.org/10.1124/dmd.122.000875
Yueping Zhang
1Bristol-Myers Squibb, United States
Shen-Jue Chen
2Bristol Myers Squibb, United States
Cliff Chen
2Bristol Myers Squibb, United States
Xue-Qing Chen
2Bristol Myers Squibb, United States
Sagnik Chatterjee
3Bristol Myers Squib, India
David J. Shuster
2Bristol Myers Squibb, United States
Heather Dexter
2Bristol Myers Squibb, United States
Laura Armstrong
2Bristol Myers Squibb, United States
Elizabeth M. Joshi
2Bristol Myers Squibb, United States
Zheng Yang
2Bristol Myers Squibb, United States
Hong Shen
4Drug Metabolism and Pharmacokinetics, Bristol Myers Squibb, United States

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Drug Metabolism and Disposition
Vol. 50, Issue 6
1 Jun 2022
OtherArticle
OATP1B down-regulation in CDCA treated monkeys
Yueping Zhang, Shen-Jue Chen, Cliff Chen, Xue-Qing Chen, Sagnik Chatterjee, David J. Shuster, Heather Dexter, Laura Armstrong, Elizabeth M. Joshi, Zheng Yang and Hong Shen
Drug Metabolism and Disposition May 30, 2022, DMD-AR-2022-000875; DOI: https://doi.org/10.1124/dmd.122.000875
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OATP1B down-regulation in CDCA treated monkeys
Yueping Zhang, Shen-Jue Chen, Cliff Chen, Xue-Qing Chen, Sagnik Chatterjee, David J. Shuster, Heather Dexter, Laura Armstrong, Elizabeth M. Joshi, Zheng Yang and Hong Shen
Drug Metabolism and Disposition May 30, 2022, DMD-AR-2022-000875; DOI: https://doi.org/10.1124/dmd.122.000875
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