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Drug Metabolism & Disposition

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Cytochrome P450 2J (CYP2J) Genes in Dogs, Cats, and Pigs Are Expressed and Encode Functional Drug-Metabolizing Enzymes

Yasuhiro Uno, Norie Murayama, Moe Ijiri, Hiroaki Kawaguchi, Osamu Yamato, Mitsuya Shiraishi, Atsushi Asano, Hiroki Teraoka, Hazuki Mizukawa, Shouta M.M. Nakayama, Yoshinori Ikenaka, Mayumi Ishizuka and Hiroshi Yamazaki
Drug Metabolism and Disposition June 14, 2022, DMD-AR-2022-000930; DOI: https://doi.org/10.1124/dmd.122.000930
Yasuhiro Uno
1Kagoshima University, Japan
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Norie Murayama
2Showa Pharmaceutical University, Japan
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Moe Ijiri
3Kagoshima Universityj, Japan
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Hiroaki Kawaguchi
4Kitasato University, Japan
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Osamu Yamato
1Kagoshima University, Japan
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Mitsuya Shiraishi
1Kagoshima University, Japan
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Atsushi Asano
1Kagoshima University, Japan
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Hiroki Teraoka
5Rakuno Gakuen University, Japan
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Hazuki Mizukawa
6Hokkaido University, Japan
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Shouta M.M. Nakayama
6Hokkaido University, Japan
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Yoshinori Ikenaka
6Hokkaido University, Japan
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Mayumi Ishizuka
7Graduate School of Veterinary Medicine, Hokkaido University, Japan
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Hiroshi Yamazaki
8Lab. Drug Metabolism and Pharmacokinetics, Showa Pharmaceutical University, Japan
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  • ORCID record for Hiroshi Yamazaki
  • For correspondence: hyamazak@ac.shoyaku.ac.jp
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Article Information

DMD-AR-2022-000930
DOI 
https://doi.org/10.1124/dmd.122.000930
PubMed 
35701183

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Published online June 14, 2022.

Copyright & Usage 
Copyright © 2020 American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Yasuhiro Uno1,
  2. Norie Murayama2,
  3. Moe Ijiri3,
  4. Hiroaki Kawaguchi4,
  5. Osamu Yamato1,
  6. Mitsuya Shiraishi1,
  7. Atsushi Asano1,
  8. Hiroki Teraoka5,
  9. Hazuki Mizukawa6,
  10. Shouta M.M. Nakayama6,
  11. Yoshinori Ikenaka6,
  12. Mayumi Ishizuka7, and
  13. Hiroshi Yamazaki8,*
  1. 1Kagoshima University, Japan
  2. 2Showa Pharmaceutical University, Japan
  3. 3Kagoshima Universityj, Japan
  4. 4Kitasato University, Japan
  5. 5Rakuno Gakuen University, Japan
  6. 6Hokkaido University, Japan
  7. 7Graduate School of Veterinary Medicine, Hokkaido University, Japan
  8. 8Lab. Drug Metabolism and Pharmacokinetics, Showa Pharmaceutical University, Japan
  1. ↵* Corresponding Author:
    Hiroshi Yamazaki, Lab. Drug Metabolism and Pharmacokinetics, Showa Pharmaceutical University, 3-3165 Higashi-tamagawa Gakuen, Machida, Tokyo, 194-8543, Japan. E-mail: hyamazak{at}ac.shoyaku.ac.jp

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Drug Metabolism and Disposition: 50 (6)
Drug Metabolism and Disposition
Vol. 50, Issue 6
1 Jun 2022
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New Dog, Cat, and Pig P450 2J Enzymes

Yasuhiro Uno, Norie Murayama, Moe Ijiri, Hiroaki Kawaguchi, Osamu Yamato, Mitsuya Shiraishi, Atsushi Asano, Hiroki Teraoka, Hazuki Mizukawa, Shouta M.M. Nakayama, Yoshinori Ikenaka, Mayumi Ishizuka and Hiroshi Yamazaki
Drug Metabolism and Disposition June 14, 2022, DMD-AR-2022-000930; DOI: https://doi.org/10.1124/dmd.122.000930

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OtherArticle

New Dog, Cat, and Pig P450 2J Enzymes

Yasuhiro Uno, Norie Murayama, Moe Ijiri, Hiroaki Kawaguchi, Osamu Yamato, Mitsuya Shiraishi, Atsushi Asano, Hiroki Teraoka, Hazuki Mizukawa, Shouta M.M. Nakayama, Yoshinori Ikenaka, Mayumi Ishizuka and Hiroshi Yamazaki
Drug Metabolism and Disposition June 14, 2022, DMD-AR-2022-000930; DOI: https://doi.org/10.1124/dmd.122.000930
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