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Quantitative CYP3A4 induction risk assessment using human hepatocytes complemented with pregnane X receptor (PXR)-activating profiles

Aynur Ekiciler, Wen Li Kelly Chen, Yan Bo, Alessandra Pugliano, Massimiliano Donzelli, Neil Parrott and Kenichi Umehara
Drug Metabolism and Disposition December 2, 2022, DMD-AR-2022-001132; DOI: https://doi.org/10.1124/dmd.122.001132
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Evaluation of CYP3A4 induction incorporating PXR activation

Aynur Ekiciler, Wen Li Kelly Chen, Yan Bo, Alessandra Pugliano, Massimiliano Donzelli, Neil Parrott and Kenichi Umehara
Drug Metabolism and Disposition December 2, 2022, DMD-AR-2022-001132; DOI: https://doi.org/10.1124/dmd.122.001132
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