Antibiotics-induced depletion of rat microbiota induces changes in the expression of host drug-processing genes and pharmacokinetic behaviors of CYPs probe drugs

Haijun Yang; Yanjuan Zhang; Rong Zhou; Tianyuan Wu; Peng Zhu; Yujie Liu; Jian Zhou; Yalan Xiong; Yanling Xiong; Honghao Zhou; Wei Zhang; Yan Shu; Xiong Li; Qing Li

doi:10.1124/dmd.122.001173

OtherArticle

Antibiotics-induced depletion of rat microbiota induces changes in the expression of host drug-processing genes and pharmacokinetic behaviors of CYPs probe drugs

Haijun Yang, Yanjuan Zhang, Rong Zhou, Tianyuan Wu, Peng Zhu, Yujie Liu, Jian Zhou, Yalan Xiong, Yanling Xiong, Honghao Zhou, Wei Zhang, Yan Shu, Xiong Li and Qing Li

Drug Metabolism and Disposition January 9, 2023, DMD-AR-2022-001173; DOI: https://doi.org/10.1124/dmd.122.001173

Haijun Yang

1Department of Clinical Pharmacology, Xiangya Hospital Central South University, China

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Yanjuan Zhang

2Central South University, China

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Rong Zhou

1Department of Clinical Pharmacology, Xiangya Hospital Central South University, China

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Tianyuan Wu

1Department of Clinical Pharmacology, Xiangya Hospital Central South University, China

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Peng Zhu

1Department of Clinical Pharmacology, Xiangya Hospital Central South University, China

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Yujie Liu

1Department of Clinical Pharmacology, Xiangya Hospital Central South University, China

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Jian Zhou

2Central South University, China

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Yalan Xiong

2Central South University, China

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Yanling Xiong

2Central South University, China

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Honghao Zhou

3Institute of Clinical Pharmacology, China

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Wei Zhang

2Central South University, China

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Yan Shu

4Pharmaceutical Sciences, University of Maryland, United States

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for Yan Shu

Xiong Li

5Key Specialty of Clinical Pharmacy, The First Affiliated Hospital of Guangdong Pharmaceutical University, China

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Qing Li

1Department of Clinical Pharmacology, Xiangya Hospital Central South University, China

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
For correspondence: liqing9251026@csu.edu.cn

Article
Figures & Data
Info & Metrics
eLetters
PDF + SI
PDF

Compose eLetter

Title *

Contents

More information about text formats

Plain text

No HTML tags allowed.
Web page addresses and e-mail addresses turn into links automatically.
Lines and paragraphs break automatically.

Author Information

Contributors
First Name and Middle Initial * First or given name, e.g. 'Peter'. Last Name * Your last, or family, name, e.g. 'MacMoody'. Email Address * Your email address, e.g. higgs-boson@gmail.com Occupation * Your role and/or occupation, e.g. 'Orthopedic Surgeon'. Affiliation * Your organization or institution (if applicable), e.g. 'Royal Free Hospital'.

Statement of Competing Interests

Competing interests? *

Yes

Please describe the competing interests

Vertical Tabs

Jump to comment:

No eLetters have been published for this article.

In this issue

Drug Metabolism and Disposition

Vol. 51, Issue 4

1 Apr 2023

Table of Contents
About the Cover
Index by author

Download PDF

Article Alerts

User Name *

Password *

Email *

Email Article

Thank you for sharing this Drug Metabolism & Disposition article.

NOTE: We request your email address only to inform the recipient that it was you who recommended this article, and that it is not junk mail. We do not retain these email addresses.

Your Email *

Your Name *

Send To *

Enter multiple addresses on separate lines or separate them with commas.

You are going to email the following Antibiotics-induced depletion of rat microbiota induces changes in the expression of host drug-processing genes and pharmacokinetic behaviors of CYPs probe drugs

Message Subject (Your Name) has forwarded a page to you from Drug Metabolism & Disposition

Message Body (Your Name) thought you would be interested in this article in Drug Metabolism & Disposition.

Your Personal Message

CAPTCHA

This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.

Citation Tools

OtherArticle

Antibiotics induces changes in the expression of rat DPGs

Haijun Yang, Yanjuan Zhang, Rong Zhou, Tianyuan Wu, Peng Zhu, Yujie Liu, Jian Zhou, Yalan Xiong, Yanling Xiong, Honghao Zhou, Wei Zhang, Yan Shu, Xiong Li and Qing Li

Drug Metabolism and Disposition January 9, 2023, DMD-AR-2022-001173; DOI: https://doi.org/10.1124/dmd.122.001173

Citation Manager Formats

BibTeX
Bookends
EasyBib
EndNote (tagged)
EndNote 8 (xml)
Medlars
Mendeley
Papers
RefWorks Tagged
Ref Manager
RIS
Zotero

OtherArticle

Antibiotics induces changes in the expression of rat DPGs

Haijun Yang, Yanjuan Zhang, Rong Zhou, Tianyuan Wu, Peng Zhu, Yujie Liu, Jian Zhou, Yalan Xiong, Yanling Xiong, Honghao Zhou, Wei Zhang, Yan Shu, Xiong Li and Qing Li

Drug Metabolism and Disposition January 9, 2023, DMD-AR-2022-001173; DOI: https://doi.org/10.1124/dmd.122.001173

Share This Article:

Tweet Widget
Facebook Like
Google Plus One

Jump to section

Article
Figures & Data
Info & Metrics
eLetters
PDF + SI
PDF

Main menu

User menu

Search

Antibiotics-induced depletion of rat microbiota induces changes in the expression of host drug-processing genes and pharmacokinetic behaviors of CYPs probe drugs

Plain text

Vertical Tabs

Jump to comment:

In this issue

Antibiotics induces changes in the expression of rat DPGs

Citation Manager Formats

Related Articles

Cited By...

More in this TOC Section

Similar Articles

Navigate

More Information

ASPET's Other Journals