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Potentiation of the Uricosuric Effect of Dotinurad by Trans-Inhibition of the Uric Acid Reabsorptive Transporter URAT1

Kazuki Fujita, Qiunan Zhu, Hiroshi Arakawa, Yoshiyuki Shirasaka and Ikumi Tamai
Drug Metabolism and Disposition August 29, 2023, DMD-AR-2023-001412; DOI: https://doi.org/10.1124/dmd.123.001412

Article Information

DMD-AR-2023-001412
DOI 
https://doi.org/10.1124/dmd.123.001412
PubMed 
37643882
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Published online August 29, 2023.
Copyright & Usage 
Copyright © 2023 American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Kazuki Fujita1,
  2. Qiunan Zhu1,
  3. Hiroshi Arakawa2,
  4. Yoshiyuki Shirasaka3, and
  5. Ikumi Tamai4,*
  1. 1Kanazawa University, Japan
  2. 2Faculty of Pharmacy, Kanazawa University, Japan
  3. 3Faculty of Pharmacy, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Japan
  4. 4Facylty of Pharmaceutical Sciences, Kanazawa University, Japan
  1. ↵* Corresponding Author:
    Ikumi Tamai, Facylty of Pharmaceutical Sciences, Kanazawa University, Kakuma-machi, Kanazawa, N/A, 920-1192, Japan. E-mail: tamai{at}p.kanazawa-u.ac.jp

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Trans-inhibition of uric acid transporter URAT1 by dotinurad

Kazuki Fujita, Qiunan Zhu, Hiroshi Arakawa, Yoshiyuki Shirasaka and Ikumi Tamai
Drug Metabolism and Disposition August 29, 2023, DMD-AR-2023-001412; DOI: https://doi.org/10.1124/dmd.123.001412
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