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Bempedoic acid unveils therapeutic potential in non-alcoholic fatty liver disease: suppression of the hepatic PXR-SLC13A5/ACLY signaling axis

Qiushuang Sun, Yating Guo, Wenjun Hu, Mengdi Zhang, Shijiao Wang, Yuanyuan Lei, Haitao Meng, Ning Li, Pengfei Xu, Zhiyu Li, Haishu Lin, Fang Huang and Zhixia Qiu
Drug Metabolism and Disposition September 8, 2023, DMD-AR-2023-001449; DOI: https://doi.org/10.1124/dmd.123.001449

Article Information

DMD-AR-2023-001449
DOI 
https://doi.org/10.1124/dmd.123.001449
PubMed 
37684055
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Published online September 8, 2023.
Copyright & Usage 
Copyright © 2023 American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Qiushuang Sun1,
  2. Yating Guo1,
  3. Wenjun Hu1,
  4. Mengdi Zhang1,
  5. Shijiao Wang1,
  6. Yuanyuan Lei1,
  7. Haitao Meng2,
  8. Ning Li1,
  9. Pengfei Xu1,
  10. Zhiyu Li1,
  11. Haishu Lin3,
  12. Fang Huang1, and
  13. Zhixia Qiu1,*
  1. 1China Pharmaceutical University, China
  2. 2Shimadzu (China), China
  3. 3Shenzhen Technology University, China
  1. ↵* Corresponding Author:
    Zhixia Qiu, China Pharmaceutical University, 639 Longmian Avenue, Jiangning District, Nanjing, China. E-mail: zxqiu{at}cpu.edu.cn

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BA improves NAFLD via suppressing the PXR-SLC13A5/ACLY axis

Qiushuang Sun, Yating Guo, Wenjun Hu, Mengdi Zhang, Shijiao Wang, Yuanyuan Lei, Haitao Meng, Ning Li, Pengfei Xu, Zhiyu Li, Haishu Lin, Fang Huang and Zhixia Qiu
Drug Metabolism and Disposition September 8, 2023, DMD-AR-2023-001449; DOI: https://doi.org/10.1124/dmd.123.001449
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