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CYP and non-CYP drug metabolizing enzyme families exhibit differential sensitivities towards pro-inflammatory cytokine modulation
Laura M. de Jong, Chandan Harpal, Dirk-Jan van den Berg, Menno Hoekstra, Nienke J Peter, Robert Rissmann, Jesse J Swen and Martijn L. Manson
Drug Metabolism and Disposition September 30, 2024, DMD-AR-2024-001867; DOI: https://doi.org/10.1124/dmd.124.001867
Laura M. de Jong
1Division of Systems Pharmacology and Pharmacy, Leiden Academic Centre for Drug Research, Netherlands
Chandan Harpal
1Division of Systems Pharmacology and Pharmacy, Leiden Academic Centre for Drug Research, Netherlands
Dirk-Jan van den Berg
1Division of Systems Pharmacology and Pharmacy, Leiden Academic Centre for Drug Research, Netherlands
Menno Hoekstra
1Division of Systems Pharmacology and Pharmacy, Leiden Academic Centre for Drug Research, Netherlands
Nienke J Peter
1Division of Systems Pharmacology and Pharmacy, Leiden Academic Centre for Drug Research, Netherlands
Robert Rissmann
2Division of Biotherapeutics, Leiden Academic Centre for Drug Research, Netherlands
Jesse J Swen
3Department of Clinical Pharmacy and Toxicology, Leiden University Medical Center, Netherlands
Martijn L. Manson
4Systems Pharmacology and Pharmacy, Leiden Academic Centre for Drug Research, Leiden University, Netherlands
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Impact of inflammation on drug metabolizing enzymes
Laura M. de Jong, Chandan Harpal, Dirk-Jan van den Berg, Menno Hoekstra, Nienke J Peter, Robert Rissmann, Jesse J Swen and Martijn L. Manson
Drug Metabolism and Disposition September 30, 2024, DMD-AR-2024-001867; DOI: https://doi.org/10.1124/dmd.124.001867
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Impact of inflammation on drug metabolizing enzymes
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Drug Metabolism and Disposition September 30, 2024, DMD-AR-2024-001867; DOI: https://doi.org/10.1124/dmd.124.001867
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