Fast Forward

DMD Fast Forward contains papers in manuscript form that have been accepted and published in DMD but have not been copyedited and have not been assigned to an issue of the journal. Copyediting may lead to some differences between the Fast Forward version and the final version. There may also be differences in the quality of the graphics. The publication date appears below each title followed by the article's unique Digital Object Identifier (DOI).

Articles

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In Vivo Functional Effects of CYP2C9 M1L, a Novel and Common Variant in the Yup'ik Alaska Native Population
Lindsay M. Henderson, Scarlett E. Hopkins, Bert B. Boyer, Timothy A. Thornton, Allan E. Rettie and Kenneth E. Thummel

Drug Metabolism and Disposition February 25, 2021, DMD-AR-2020-000301; DOI: https://doi.org/10.1124/dmd.120.000301
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Clinical investigation of metabolic and renal clearance pathways contributing to the elimination of fevipiprant using probenecid as perpetrator
H. Markus Weiss, Thomas Langenickel, Meredith Cain, Swarupa Kulkarni, Bharti Shah, Janardhana Vemula, Gholamreza Rahmanzadeh and Birk Poller

Drug Metabolism and Disposition February 25, 2021, DMD-AR-2020-000273; DOI: https://doi.org/10.1124/dmd.120.000273
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Evaluation of Tissue Binding in 3 Tissues Across 5 Species, and Prediction of Volume of Distribution from Plasma Protein and Tissue Binding
Frederick Hsu, Yi-Chen Chen and Fabio Broccatelli

Drug Metabolism and Disposition February 25, 2021, DMD-AR-2020-000337; DOI: https://doi.org/10.1124/dmd.120.000337
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Revisiting nonlinear bosentan pharmacokinetics by PBPK modeling: Target binding, albeit not a major contributor to nonlinearity, can offer prediction of target occupancy
Satoshi Koyama, Kota Toshimoto, Wooin Lee, Yasunori Aoki and Yuichi Sugiyama

Drug Metabolism and Disposition February 8, 2021, DMD-AR-2020-000023; DOI: https://doi.org/10.1124/dmd.120.000023
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Maternal and fetal pharmacokinetic analysis of cannabidiol during pregnancy in mice
Wataru Ochiai, Satoshi Kitaoka, Taisuke Kawamura, Jo Hatogai, Shohei Harada, Misa Iizuka, Mashu Ariumi, Seiya Takano, Tomomi Nagai, Masanaho Sasatsu and Kiyoshi Sugiyama

Drug Metabolism and Disposition February 2, 2021, DMD-AR-2020-000270; DOI: https://doi.org/10.1124/dmd.120.000270
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Functional proliferating human hepatocytes: in vitro hepatocyte model for drug metabolism, excretion and toxicity
Shida Qiao, Sisi Feng, Zhitao Wu, Ting He, Chen Ma, Zhaoliang Peng, E Tian and Guoyu Pan

Drug Metabolism and Disposition February 1, 2021, DMD-AR-2020-000275; DOI: https://doi.org/10.1124/dmd.120.000275
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Function and Expression of Bile Salt Export Pump in Suspension Human Hepatocytes
Paresh P. Chothe, Rachel Pemberton and Niresh Hariparsad

Drug Metabolism and Disposition January 20, 2021, DMD-AR-2020-000057; DOI: https://doi.org/10.1124/dmd.120.000057
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In vitro evidence of potential interactions between CYP2C8 and candesartan acyl-β-D-glucuronide in the liver
Yurie Katsube, Masayuki Tsujimoto, Hiroyoshi Koide, Daiki Hira, Yoshito Ikeda, Tetsuya Minegaki, Shin-ya Morita, Tomohiro Terada and Kohshi Nishiguchi

Drug Metabolism and Disposition January 14, 2021, DMD-AR-2020-000126; DOI: https://doi.org/10.1124/dmd.120.000126
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Role of human AADAC on hydrolysis of eslicarbazepine acetate and effects of AADAC genetic polymorphisms on hydrolase activity
Keiya Hirosawa, Tatsuki Fukami, Kiyomichi Tashiro, Yoshiyuki Sakai, Fumiya Kisui, Masataka Nakano and Miki Nakajima

Drug Metabolism and Disposition January 14, 2021, DMD-AR-2020-000295; DOI: https://doi.org/10.1124/dmd.120.000295

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