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Drug Metabolism & Disposition

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Latest Articles

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    Activation/deactivation of anticancer drugs by CYP3A4: influencing factors for personalized cancer therapy
    Fengling Wang, Xue Zhang, Yanyan Wang, Yunna Chen, Huiyu Lu, Xiangyun Meng, Xi Ye and Weidong Chen
    Drug Metabolism and Disposition February 2, 2023, DMD-MR-2022-001131; DOI: https://doi.org/10.1124/dmd.122.001131
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    Exploring the Pharmacokinetic Mysteries of the Liver: Application of Series Compartment Models of Hepatic Elimination
    Xiaonan Li and William J Jusko
    Drug Metabolism and Disposition February 2, 2023, DMD-AR-2022-001190; DOI: https://doi.org/10.1124/dmd.122.001190
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    Drug Transporters at the Human Blood-Testis Barrier
    Raymond K. Hau, Stephen H. Wright and Nathan J. Cherrington
    Drug Metabolism and Disposition February 2, 2023, DMD-MR-2022-001186; DOI: https://doi.org/10.1124/dmd.122.001186
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    A Physiological-Based Pharmacokinetic Model Embedded with a Target-Mediated Drug Disposition Mechanism Can Characterize Single-Dose Warfarin Pharmacokinetic Profiles in Subjects with Various CYP2C9 Genotypes under Different Cotreatments
    Shen Cheng, Darcy R. Flora, Allan E. Rettie, Richard C. Brundage and Timothy S. Tracy
    Drug Metabolism and Disposition February 2023, 51 (2) 257-267; DOI: https://doi.org/10.1124/dmd.122.001048
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    Detection and characterization of in vitro payload-containing catabolites of non-cleavable ADCs by high-resolution mass spectrometry and multiple data-mining tools
    Tingting Cai, Liqi Shi, Huihui Guo, Ruixing Li, Weiqun Cao, Liang Shen, Mingshe Zhu and Yi Tao
    Drug Metabolism and Disposition January 27, 2023, DMD-AR-2022-001135; DOI: https://doi.org/10.1124/dmd.122.001135
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    Phenobarbital in Nuclear Receptor Activation: An Update
    Shuaiqian Men and Hongbing Wang
    Drug Metabolism and Disposition February 2023, 51 (2) 210-218; DOI: https://doi.org/10.1124/dmd.122.000859
  • Microbial Metabolites as Ligands to Xenobiotic Receptors: Chemical Mimicry as Potential Drugs of the Future
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    Microbial Metabolites as Ligands to Xenobiotic Receptors: Chemical Mimicry as Potential Drugs of the Future
    Zdeněk Dvořák, Hao Li and Sridhar Mani
    Drug Metabolism and Disposition February 2023, 51 (2) 219-227; DOI: https://doi.org/10.1124/dmd.122.000860
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    Pharmacokinetic Interactions of a Licorice Dietary Supplement with Cytochrome P450 Enzymes in Female Participants
    Jialin Liu, Suzanne Banuvar, Marlos Viana, Elena Barengolts, Shao-Nong Chen, Guido F. Pauli and Richard B. van Breemen
    Drug Metabolism and Disposition February 2023, 51 (2) 199-204; DOI: https://doi.org/10.1124/dmd.122.001050
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    The Function of Xenobiotic Receptors in Metabolic Diseases
    Jinhang Zhang, Qingyi Jia, Yanping Li and Jinhan He
    Drug Metabolism and Disposition February 2023, 51 (2) 237-248; DOI: https://doi.org/10.1124/dmd.122.000862
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    Special Section on Xenobiotic Receptors–Editorial
    Xiao-bo Zhong and Yurong Lai
    Drug Metabolism and Disposition February 2023, 51 (2) 205-206; DOI: https://doi.org/10.1124/dmd.122.001207

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