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Characterization of Enzymes Involved in Nintedanib Metabolism in Humans
Shimon Nakashima, Rei Sato, Tatsuki Fukami, Takashi Kudo, Shiori Hashiba, Gaku Morinaga, Masataka Nakano, Eva Ludwig-Schwellinger, Akiko Matsui, Naoki Ishiguro, Thomas Ebner and Miki Nakajima

Drug Metabolism and Disposition March 16, 2023, DMD-AR-2022-001113; DOI: https://doi.org/10.1124/dmd.122.001113
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Mechanistic Investigation of the Time-Dependent Aldehyde Oxidase Inhibitor Hydralazine
J Paige Barnes, Shaoyun M Yang, Taylor S Thompson, Caithlyne M Guevarra, Shaniya S Pleasant, Tri Q. Do and Rachel D Crouch

Drug Metabolism and Disposition March 15, 2023, DMD-AR-2023-001257; DOI: https://doi.org/10.1124/dmd.123.001257
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Predicting in vivo Target Occupancy (TO) Profiles via PBPK-TO Modeling of Warfarin Pharmacokinetics in Blood: Importance of Low Dose Data and Prediction of Stereoselective Target Interactions
Wooin Lee, Min-Soo Kim, Jiyoung Kim, Yasunori Aoki and Yuichi Sugiyama

Drug Metabolism and Disposition March 13, 2023, DMD-AR-2022-000968; DOI: https://doi.org/10.1124/dmd.122.000968
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Challenges and opportunities in P450 research on the eye
Irina A. Pikuleva

Drug Metabolism and Disposition March 13, 2023, DMD-MR-2022-001072; DOI: https://doi.org/10.1124/dmd.122.001072
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Impact of direction of transport on the evaluation of substrate recognition of mouse multidrug and toxin extrusion protein 1 (mMate1)
Asami Saito, Tomoko Kito, Naoki Ishiguro, Masahito Takatani, Takashi Kudo, Bojan Bister and Hiroyuki Kusuhara

Drug Metabolism and Disposition March 7, 2023, DMD-AR-2022-001115; DOI: https://doi.org/10.1124/dmd.122.001115
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Fifty years of aryl hydrocarbon receptor research as reflected in the pages of Drug Metabolism and Disposition
David S. Riddick

Drug Metabolism and Disposition March 7, 2023, DMD-MR-2022-001009; DOI: https://doi.org/10.1124/dmd.122.001009
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Activation/deactivation of anticancer drugs by CYP3A4: influencing factors for personalized cancer therapy
Fengling Wang, Xue Zhang, Yanyan Wang, Yunna Chen, Huiyu Lu, Xiangyun Meng, Xi Ye and Weidong Chen

Drug Metabolism and Disposition March 7, 2023, DMD-MR-2022-001131; DOI: https://doi.org/10.1124/dmd.122.001131
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Identification of PXR activators from Uncaria rhynchophylla (Gou Teng) and Uncaria tomentosa (Cat's Claw)
Saifei Lei, Jie Lu, Anqi Cheng, Zahir Hussain, Kevin Tidgewell, Junjie Zhu and Xiaochao Ma

Drug Metabolism and Disposition March 7, 2023, DMD-AR-2022-001234; DOI: https://doi.org/10.1124/dmd.122.001234
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Detection and characterization of in vitro payload-containing catabolites of non-cleavable ADCs by high-resolution mass spectrometry and multiple data-mining tools
Tingting Cai, Liqi Shi, Huihui Guo, Ruixing Li, Weiqun Cao, Liang Shen, Mingshe Zhu and Yi Tao

Drug Metabolism and Disposition March 7, 2023, DMD-AR-2022-001135; DOI: https://doi.org/10.1124/dmd.122.001135
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Drug Transporters at the Human Blood-Testis Barrier
Raymond K. Hau, Stephen H. Wright and Nathan J. Cherrington

Drug Metabolism and Disposition March 7, 2023, DMD-MR-2022-001186; DOI: https://doi.org/10.1124/dmd.122.001186

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