Latest Articles

Article Type

You have access
Biotransformation of the Novel Myeloperoxidase Inhibitor AZD4831 in Preclinical Species and Humans
Ulrik Jurva, Lars Weidolf, Ann-Sofie Sandinge, Carina Leandersson, Anja Ekdahl, Xue-Qing Li, Thomas Antonsson, Johan Sundell, Kristina Westerlund, Carl Amilon, Tord Inghardt and V. Sashi Gopaul

Drug Metabolism and Disposition February 28, 2023, DMD-AR-2022-001099; DOI: https://doi.org/10.1124/dmd.122.001099
You have access
Application of Accelerator Mass Spectrometry to Characterize the Mass Balance Recovery and Disposition of AZD4831, a Novel Myeloperoxidase Inhibitor, Following Administration of an Oral Radiolabeled Microtracer Dose in Humans
Chandrali Bhattacharya, Ann-Sofie Sandinge, Ryan A. Bragg, Maria Heijer, Jingjing Yan, Linda C. Andersson, Ulrik Jurva, Marta Pelay-Gimeno, Wouter H.J. Vaes, Rianne A.F. de Ligt, Malin Gränfors, Carl Amilon, Eva-Lotte Lindstedt, Somasekhara R. Menakuru, Pavlo Garkaviy, Lars Weidolf and V. Sashi Gopaul

Drug Metabolism and Disposition February 28, 2023, DMD-AR-2022-001100; DOI: https://doi.org/10.1124/dmd.122.001100
You have access
Unusual Biotransformation Reactions of Drugs and Drug Candidates
Emre M. Isin

Drug Metabolism and Disposition February 28, 2023, DMD-MR-2021-000744; DOI: https://doi.org/10.1124/dmd.121.000744
You have access
Relevance of Human Aldoketoreductases and Microbial β-Glucuronidases in Testosterone Disposition
Abdul Basit, John K. Amory, Vijaya Saradhi Mettu, Cindy Yanfei Li, Scott Heyward, Parth B. Jariwala, Matthew R. Redinbo and Bhagwat Prasad

Drug Metabolism and Disposition February 28, 2023, DMD-AR-2022-000975; DOI: https://doi.org/10.1124/dmd.122.000975
You have access
The Unique Human N10-Glucuronidated Metabolite Formation from Olanzapine in Chimeric NOG-TKm30 Mice with Humanized Livers
Shotaro Uehara, Yuichiro Higuchi, Nao Yoneda, Hiroaki Kato, Hiroshi Yamazaki and Hiroshi Suemizu

Drug Metabolism and Disposition February 28, 2023, DMD-AR-2022-001102; DOI: https://doi.org/10.1124/dmd.122.001102
You have access
Biotransformation of efavirenz and proteomic analysis of P450s and UGTs in mouse, macaque, and human brain-derived in vitro systems
Abigail M. Wheeler, Benjamin C. Orsburn and Namandje N. Bumpus

Drug Metabolism and Disposition February 28, 2023, DMD-AR-2022-001195; DOI: https://doi.org/10.1124/dmd.122.001195
You have access
Predictive Performance of Physiologically Based Pharmacokinetic Modelling of Beta-Lactam Antibiotic Concentrations in Adipose, Bone and Muscle Tissues
Pieter-Jan De Sutter, Pieter De Cock, Trevor N. Johnson, Helen Musther, Elke Gasthuys and An Vermeulen

Drug Metabolism and Disposition February 28, 2023, DMD-AR-2022-001129; DOI: https://doi.org/10.1124/dmd.122.001129
You have access
CYP3A4 and CYP3A5 expression is regulated by CYP3A4*1G in CRISPR/Cas9 edited HepG2 cells
Weihong Yang, Huan Zhao, Yaojie Dou, Pei Wang, Qi Chang, Xiaomeng Qiao, Xiaofei Wang, Chen Xu, Zhe Zhang and Lirong Zhang

Drug Metabolism and Disposition February 28, 2023, DMD-AR-2022-001111; DOI: https://doi.org/10.1124/dmd.122.001111
You have access
Process and System Clearances in Pharmacokinetic Models: Our Basic Clearance Concepts are Correct
Ken Korzekwa and Swati Nagar

Drug Metabolism and Disposition February 28, 2023, DMD-MR-2022-001060; DOI: https://doi.org/10.1124/dmd.122.001060
You have access
Antibiotics-induced depletion of rat microbiota induces changes in the expression of host drug-processing genes and pharmacokinetic behaviors of CYPs probe drugs
Haijun Yang, Yanjuan Zhang, Rong Zhou, Tianyuan Wu, Peng Zhu, Yujie Liu, Jian Zhou, Yalan Xiong, Yanling Xiong, Honghao Zhou, Wei Zhang, Yan Shu, Xiong Li and Qing Li

Drug Metabolism and Disposition February 28, 2023, DMD-AR-2022-001173; DOI: https://doi.org/10.1124/dmd.122.001173

Main menu

User menu

Search

Latest Articles

Pages

Navigate

More Information

ASPET's Other Journals