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Drug Metabolism & Disposition

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    Perfluorinated Carboxylic Acids with Increasing Carbon Chain Lengths Upregulate Amino Acid Transporters and Modulate Compensatory Response of Xenobiotic Transporters in HepaRG Cells
    Joe Jongpyo Lim, Youjun Suh, Elaine M. Faustman and Julia Yue Cui
    Drug Metabolism and Disposition October 2022, 50 (10) 1396-1413; DOI: https://doi.org/10.1124/dmd.121.000477
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    Role and Regulation of Hepatobiliary ATP-Binding Cassette Transporters during Chemical-Induced Liver Injury
    Carolina I. Ghanem and Jose E. Manautou
    Drug Metabolism and Disposition October 2022, 50 (10) 1376-1388; DOI: https://doi.org/10.1124/dmd.121.000450
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    Effect of Chronic Cadmium Exposure on Brain and Liver Transporters and Drug-Metabolizing Enzymes in Male and Female Mice Genetically Predisposed to Alzheimer’s Disease
    Hao Wang, Liang Zhang, Zhengui Xia and Julia Yue Cui
    Drug Metabolism and Disposition October 2022, 50 (10) 1414-1428; DOI: https://doi.org/10.1124/dmd.121.000453
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    Special Section on Mechanistic and Translational Research on Transporters in Toxicology–Editorial
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    Drug Metabolism and Disposition October 2022, 50 (10) 1361-1363; DOI: https://doi.org/10.1124/dmd.122.001042
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    Physiologically Based Pharmacokinetic Modeling To Predict Drug-Biologic Interactions with Cytokine Modulators: Are These Relevant and Is Interleukin-6 Enough?
    Kuan-Fu Chen, Hannah M. Jones and Katherine L. Gill
    Drug Metabolism and Disposition October 2022, 50 (10) 1322-1331; DOI: https://doi.org/10.1124/dmd.122.000926
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    Inhibition of Cytochrome P450 2J2-Mediated Metabolism of Rivaroxaban and Arachidonic Acid by Ibrutinib and Osimertinib
    Ziteng Wang and Eric Chun Yong Chan
    Drug Metabolism and Disposition October 2022, 50 (10) 1332-1341; DOI: https://doi.org/10.1124/dmd.122.000928
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    Isolation and Identification of 3,4-Seco-Solanidine-3,4-dioic Acid as a Urinary Biomarker of CYP2D6 Activity
    Andrew C Behrle, Justin Douglas, J. Steven Leeder and Leon van Haandel
    Drug Metabolism and Disposition October 2022, 50 (10) 1342-1351; DOI: https://doi.org/10.1124/dmd.122.000957
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    Mesenchymal Stem Cell Fates in Murine Acute Liver Injury and Chronic Liver Fibrosis Induced by Carbon Tetrachloride
    Chenhui Ma, Li Han, Jiajun Wu, Feng Tang, Qiangqiang Deng, Ting He, Zhitao Wu, Chen Ma, Wei Huang, Ruimin Huang and Guoyu Pan
    Drug Metabolism and Disposition October 2022, 50 (10) 1352-1360; DOI: https://doi.org/10.1124/dmd.122.000958
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    Transporter-Enzyme Interplay in the Pharmacokinetics of PF-06835919, a First-In-Class Ketohexokinase Inhibitor for Metabolic Disorders and Nonalcoholic Fatty Liver Disease
    Yan Weng, Kari R. Fonseca, Yi-an Bi, Sumathy Mathialagan, Keith Riccardi, Elaine Tseng, Andrew J. Bessire, Mathew A. Cerny, David A. Tess, A. David Rodrigues, Amit S. Kalgutkar, John Litchfield, Li Di and Manthena V. S. Varma
    Drug Metabolism and Disposition September 2022, 50 (9) 1312-1321; DOI: https://doi.org/10.1124/dmd.122.000953
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    Clinical Applications and the Roles of Transporters in Disposition, Tumor Targeting, and Tissue Toxicity of meta-Iodobenzylguanidine
    Antonio J. López Quiñones, Letícia Salvador Vieira and Joanne Wang
    Drug Metabolism and Disposition September 2022, 50 (9) 1218-1227; DOI: https://doi.org/10.1124/dmd.121.000707

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