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Drug Metabolism & Disposition

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Latest Articles

  • Cell Type–Specific Roles of CD38 in the Interactions of Isoniazid with NAD<sup>+</sup> in the Liver
    You have access
    Cell Type–Specific Roles of CD38 in the Interactions of Isoniazid with NAD+ in the Liver
    Junjie Zhu, Jie Lu, Hung-Chun Tung, Ke Liu, Jianhua Li, Denis M. Grant, Wen Xie and Xiaochao Ma
    Drug Metabolism and Disposition December 2020, 48 (12) 1372-1379; DOI: https://doi.org/10.1124/dmd.120.000139
  • You have access
    Correction to “Characterization of Seasonal Pharmacokinetic Variability in Woodchucks”
    Drug Metabolism and Disposition December 2020, 48 (12) 1348-1349; DOI: https://doi.org/10.1124/dmd.120.000140err
  • You have access
    In Vitro Characterization of Ertugliflozin Metabolism by UDP-Glucuronosyltransferase and Cytochrome P450 Enzymes
    Kimberly Lapham, Ernesto Callegari, Julie Cianfrogna, Jian Lin, Mark Niosi, Christine C. Orozco, Raman Sharma and Theunis C. Goosen
    Drug Metabolism and Disposition December 2020, 48 (12) 1350-1363; DOI: https://doi.org/10.1124/dmd.120.000171
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    Site-Directed Mutagenesis at the Molybdenum Pterin Cofactor Site of the Human Aldehyde Oxidase: Interrogating the Kinetic Differences Between Human and Cynomolgus Monkey
    Armina Abbasi, Carolyn A. Joswig-Jones and Jeffrey P. Jones
    Drug Metabolism and Disposition December 2020, 48 (12) 1364-1371; DOI: https://doi.org/10.1124/dmd.120.000187
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    Correction to “Gestational Age–Dependent Abundance of Human Placental Transporters as Determined by Quantitative Targeted Proteomics”
    Drug Metabolism and Disposition December 2020, 48 (12) 1347; DOI: https://doi.org/10.1124/dmd.120.000067err
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    In Vitro Investigation, Pharmacokinetics, and Disposition of Imeglimin, a Novel Oral Antidiabetic Drug, in Preclinical Species and Humans
    Chevalier Clémence, Pascale Fouqueray and Bolze Sébastien
    Drug Metabolism and Disposition December 2020, 48 (12) 1330-1346; DOI: https://doi.org/10.1124/dmd.120.000154
  • Open Access
    Revefenacin Absorption, Metabolism, and Excretion in Healthy Subjects and Pharmacological Activity of Its Major Metabolite
    David L. Bourdet, Suresh Yeola, Sharath S. Hegde, Pierre-Jean Colson, Chris N. Barnes and Marie T. Borin
    Drug Metabolism and Disposition December 2020, 48 (12) 1312-1320; DOI: https://doi.org/10.1124/dmd.120.000103
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    Histone Methyltransferase G9a Regulates Expression of Nuclear Receptors and Cytochrome P450 Enzymes in HepaRG Cells at Basal Level and in Fatty Acid Induced Steatosis
    Parimal Pande, Xiao-bo Zhong and Warren W. Ku
    Drug Metabolism and Disposition December 2020, 48 (12) 1321-1329; DOI: https://doi.org/10.1124/dmd.120.000195
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    In Vitro Hepatic Uptake in Human and Monkey Hepatocytes in the Presence and Absence of Serum Protein and Its In Vitro to In Vivo Extrapolation
    Xiaomin Liang, Yeojin Park, Natalie DeForest, Jia Hao, Xiaofeng Zhao, Congrong Niu, Kelly Wang, Bill Smith and Yurong Lai
    Drug Metabolism and Disposition December 2020, 48 (12) 1283-1292; DOI: https://doi.org/10.1124/dmd.120.000163
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    Scaling Factors for Clearance in Adult Liver Cirrhosis
    Eman El-Khateeb, Brahim Achour, Daniel Scotcher, Zubida M. Al-Majdoub, Varinder Athwal, Jill Barber and Amin Rostami-Hodjegan
    Drug Metabolism and Disposition December 2020, 48 (12) 1271-1282; DOI: https://doi.org/10.1124/dmd.120.000152

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