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Effect of Human Plasma on Hepatic Uptake of Organic Anion–Transporting Polypeptide 1B Substrates: Studies Using Transfected Cells and Primary Human Hepatocytes
Yi-an Bi, Sangwoo Ryu, David A. Tess, A. David Rodrigues and Manthena V. S. Varma

Drug Metabolism and Disposition January 2021, 49 (1) 72-83; DOI: https://doi.org/10.1124/dmd.120.000134
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Characterization of the Human Intestinal Drug Transport with Ussing Chamber System Incorporating Freshly Isolated Human Jejunum
Kazuyoshi Michiba, Kazuya Maeda, Ko Kurimori, Tsuyoshi Enomoto, Osamu Shimomura, Tomoyo Takeuchi, Hiroyuki Nishiyama, Tatsuya Oda and Hiroyuki Kusuhara

Drug Metabolism and Disposition January 2021, 49 (1) 84-93; DOI: https://doi.org/10.1124/dmd.120.000138
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Effect of Gender and Various Diets on Bile Acid Profile and Related Genes in Mice
Chong Ma, Ying Guo and Curtis D. Klaassen

Drug Metabolism and Disposition January 2021, 49 (1) 62-71; DOI: https://doi.org/10.1124/dmd.120.000166
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Extension of the Mechanistic Tissue Distribution Model of Rodgers and Rowland by Systematic Incorporation of Lysosomal Trapping: Impact on Unbound Partition Coefficient and Volume of Distribution Predictions in the Rat
Maximilian V. Schmitt, Andreas Reichel, Xiaohui Liu, Gert Fricker and Philip Lienau

Drug Metabolism and Disposition January 2021, 49 (1) 53-61; DOI: https://doi.org/10.1124/dmd.120.000161
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Editorial
Xinxin Ding

Drug Metabolism and Disposition January 2021, 49 (1) 1-2; DOI: https://doi.org/10.1124/dmd.120.000298
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Regulation of Intestinal UDP-Glucuronosyltransferase 1A1 by the Farnesoid X Receptor Agonist Obeticholic Acid Is Controlled by Constitutive Androstane Receptor through Intestinal Maturation
André A. Weber, Elvira Mennillo, Xiaojing Yang, Lori W.E. van der Schoor, Johan W. Jonker, Shujuan Chen and Robert H. Tukey

Drug Metabolism and Disposition January 2021, 49 (1) 12-19; DOI: https://doi.org/10.1124/dmd.120.000240
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Label-Free Quantitative Proteomics and Substrate-Based Mass Spectrometry Imaging of Xenobiotic Metabolizing Enzymes in Ex Vivo Human Skin and a Human Living Skin Equivalent Model
Narciso Couto, Jillian R.A. Newton, Cristina Russo, Esther Karunakaran, Brahim Achour, Zubida M. Al-Majdoub, James Sidaway, Amin Rostami-Hodjegan, Malcolm R. Clench and Jill Barber

Drug Metabolism and Disposition January 2021, 49 (1) 39-52; DOI: https://doi.org/10.1124/dmd.120.000168
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Downregulation of CYP1A2, CYP2B6, and CYP3A4 in Human Hepatocytes by Prolyl Hydroxylase Domain 2 Inhibitors via Hypoxia-Inducible Factor-α Stabilization
Hiroki Takano, Jun-ichi Yamaguchi, Sota Kato, Makoto Hamada, Mika Tada and Hiromi Endo

Drug Metabolism and Disposition January 2021, 49 (1) 20-30; DOI: https://doi.org/10.1124/dmd.120.000124
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Disposition and Metabolism of [¹⁴C]Lemborexant in Healthy Human Subjects and Characterization of Its Circulating Metabolites
Takashi Ueno, Tomomi Ishida, Jagadeesh Aluri, Michiyuki Suzuki, Carsten T. Beuckmann, Takaaki Kameyama, Shoji Asakura and Kazutomi Kusano

Drug Metabolism and Disposition January 2021, 49 (1) 31-38; DOI: https://doi.org/10.1124/dmd.120.000229
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Functional Investigation of Solute Carrier Family 35, Member F2, in Three Cellular Models of the Primate Blood-Brain Barrier
Tatsuki Mochizuki, Tadahaya Mizuno, Toshiki Kurosawa, Tomoko Yamaguchi, Kei Higuchi, Yuma Tega, Yoshitane Nozaki, Kenji Kawabata, Yoshiharu Deguchi and Hiroyuki Kusuhara

Drug Metabolism and Disposition January 2021, 49 (1) 3-11; DOI: https://doi.org/10.1124/dmd.120.000115

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