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Drug Metabolism & Disposition

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Latest Articles

  • Multiomics Profiling Reveals Protective Function of <em>Schisandra</em> Lignans against Acetaminophen-Induced Hepatotoxicity
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    Multiomics Profiling Reveals Protective Function of Schisandra Lignans against Acetaminophen-Induced Hepatotoxicity
    Caixia Yan, Huimin Guo, Qingqing Ding, Yuhao Shao, Dian Kang, Tengjie Yu, Changjian Li, Haoran Huang, Yisha Du, He Wang, Kangrui Hu, Lin Xie, Guangji Wang and Yan Liang
    Drug Metabolism and Disposition October 2020, 48 (10) 1092-1103; DOI: https://doi.org/10.1124/dmd.120.000083
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    In Vitro Human Cell–Based Experimental Models for the Evaluation of Enteric Metabolism and Drug Interaction Potential of Drugs and Natural Products
    Albert P. Li
    Drug Metabolism and Disposition October 2020, 48 (10) 980-992; DOI: https://doi.org/10.1124/dmd.120.000053
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    Organic Cation Transporter 1 and 3 Contribute to the High Accumulation of Dehydrocorydaline in the Heart
    Yingchun Chen, Cui Li, Yaodong Yi, Weijuan Du, Huidi Jiang, Su Zeng and Hui Zhou
    Drug Metabolism and Disposition October 2020, 48 (10) 1074-1083; DOI: https://doi.org/10.1124/dmd.120.000025
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    Modulation of Major Human Liver Microsomal Cytochromes P450 by Component Alkaloids of Goldenseal: Time-Dependent Inhibition and Allosteric Effects
    Matthew G. McDonald, Dan-Dan Tian, Kenneth E. Thummel, Mary F. Paine and Allan E. Rettie
    Drug Metabolism and Disposition October 2020, 48 (10) 1018-1027; DOI: https://doi.org/10.1124/dmd.120.091041
  • Multidrug Resistance–Associated Protein 3 Is Responsible for the Efflux Transport of Curcumin Glucuronide from Hepatocytes to the Blood
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    Multidrug Resistance–Associated Protein 3 Is Responsible for the Efflux Transport of Curcumin Glucuronide from Hepatocytes to the Blood
    Yu-Meng Jia, Ting Zhu, Huan Zhou, Jin-Zi Ji, Ting Tai and Hong-Guang Xie
    Drug Metabolism and Disposition October 2020, 48 (10) 966-971; DOI: https://doi.org/10.1124/dmd.119.089193
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    Predicting the Potential for Cannabinoids to Precipitate Pharmacokinetic Drug Interactions via Reversible Inhibition or Inactivation of Major Cytochromes P450
    Sumit Bansal, Neha Maharao, Mary F. Paine and Jashvant D. Unadkat
    Drug Metabolism and Disposition October 2020, 48 (10) 1008-1017; DOI: https://doi.org/10.1124/dmd.120.000073
  • Open Access
    A New Data Repository for Pharmacokinetic Natural Product-Drug Interactions: From Chemical Characterization to Clinical Studies
    Caroline Birer-Williams, Brandon T. Gufford, Eric Chou, Marijanel Alilio, Sidney VanAlstine, Rachael E. Morley, Jeannine S. McCune, Mary F. Paine and Richard D. Boyce
    Drug Metabolism and Disposition October 2020, 48 (10) 1104-1112; DOI: https://doi.org/10.1124/dmd.120.000054
  • The Effects of Traditional Chinese Medicine on P-Glycoprotein–Mediated Multidrug Resistance and Approaches for Studying the Herb–P-Glycoprotein Interactions
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    The Effects of Traditional Chinese Medicine on P-Glycoprotein–Mediated Multidrug Resistance and Approaches for Studying the Herb–P-Glycoprotein Interactions
    Yuhong Cao, Yiwei Shi, Ying Cai, Zhanying Hong and Yifeng Chai
    Drug Metabolism and Disposition October 2020, 48 (10) 972-979; DOI: https://doi.org/10.1124/dmd.120.000050
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    Human Amyloid-β40 Kinetics after Intravenous and Intracerebroventricular Injections and Calcitriol Treatment in Rats In Vivo
    H. Benson Peng, Keumhan Noh, Sophie R. Pan, Victor Saldivia, Sylvia Serson, Anja Toscan, Inés A.M. de Lannoy and K. Sandy Pang
    Drug Metabolism and Disposition October 2020, 48 (10) 944-955; DOI: https://doi.org/10.1124/dmd.120.090886
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    Quantification of Neonatal Fc Receptor and Beta-2 Microglobulin in Human Liver Tissues by Ultraperformance Liquid Chromatography–Multiple Reaction Monitoring–based Targeted Quantitative Proteomics for Applications in Biotherapeutic Physiologically-based Pharmacokinetic Models
    Xiazi Qiu and Michael Zhuo Wang
    Drug Metabolism and Disposition October 2020, 48 (10) 925-933; DOI: https://doi.org/10.1124/dmd.120.000075

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