Latest Articles

Article Type

Open Access
Novel Approaches to Characterize Individual Drug Metabolism and Advance Precision Medicine
Klarissa D. Jackson, Brahim Achour, Jonghwa Lee, Raeanne M. Geffert, Jessica L. Beers and Bethany D. Latham

Drug Metabolism and Disposition October 2023, 51 (10) 1238-1253; DOI: https://doi.org/10.1124/dmd.122.001066
You have access
The Important Role of Transporter Structures in Drug Disposition, Efficacy, and Toxicity
Tingting Fu, Su Zeng, Qingchuan Zheng and Feng Zhu

Drug Metabolism and Disposition October 2023, 51 (10) 1316-1323; DOI: https://doi.org/10.1124/dmd.123.001275
You have access
Interaction of Human OATP1B1 with PDZK1 Is Required for Its Trafficking to the Hepatocyte Plasma Membrane
Pijun Wang, John W. Murray and Allan W. Wolkoff

Drug Metabolism and Disposition October 2023, 51 (10) 1342-1349; DOI: https://doi.org/10.1124/dmd.123.001248
You have access
Characterization of Pharmacokinetics, Biotransformation and Elimination of Pomotrelvir Orally Administered in Healthy Male Adults Using Two [¹⁴C]-labeled Microtracers with Separate Labeling Positions
Ziping Yang, Shekman L. Wong, David Cha, David Wilfret, David Turnquist, Andrew Plummer, Eric van Ingen and Brian P Kearney

Drug Metabolism and Disposition September 8, 2023, DMD-AR-2023-001439; DOI: https://doi.org/10.1124/dmd.123.001439
You have access
Bempedoic acid unveils therapeutic potential in non-alcoholic fatty liver disease: suppression of the hepatic PXR-SLC13A5/ACLY signaling axis
Qiushuang Sun, Yating Guo, Wenjun Hu, Mengdi Zhang, Shijiao Wang, Yuanyuan Lei, Haitao Meng, Ning Li, Pengfei Xu, Zhiyu Li, Haishu Lin, Fang Huang and Zhixia Qiu

Drug Metabolism and Disposition September 8, 2023, DMD-AR-2023-001449; DOI: https://doi.org/10.1124/dmd.123.001449
You have access
Heterodimerization of human UDP-glucuronosyltransferase (UGT) 1A9 and UGT2B7 alters their glucuronidation activities
Jia Xue, Jiayi Yin, Jing Nie, Huidi Jiang, Haitao Zhang and Su Zeng

Drug Metabolism and Disposition August 29, 2023, DMD-AR-2023-001369; DOI: https://doi.org/10.1124/dmd.123.001369
You have access
Potentiation of the Uricosuric Effect of Dotinurad by Trans-Inhibition of the Uric Acid Reabsorptive Transporter URAT1
Kazuki Fujita, Qiunan Zhu, Hiroshi Arakawa, Yoshiyuki Shirasaka and Ikumi Tamai

Drug Metabolism and Disposition August 29, 2023, DMD-AR-2023-001412; DOI: https://doi.org/10.1124/dmd.123.001412
You have access
Pharmacokinetics and Absorption, Distribution, Metabolism and Excretion of RGLS4326 in Mouse and Monkey, an anti-miR-17 Oligonucleotide for the Treatment of Polycystic Kidney Disease
Amin Kamel, Tate Owen, Izaiah Cole, Tania Valencia and Edmund C Lee

Drug Metabolism and Disposition August 29, 2023, DMD-AR-2023-001446; DOI: https://doi.org/10.1124/dmd.123.001446
You have access
Prediction of Drug-Drug Interactions with Ensartinib as a Time Dependent CYP3A Inhibitor Using Physiologically Based Pharmacokinetic Model
Xiaowen Wang, Yiqun Yu, Hongrui Liu, Fengjiao Bu, Chunying Shen, Qingfeng He, Xiao Zhu, Pin Jiang, Bing Han and Xiaoqiang Xiang

Drug Metabolism and Disposition August 29, 2023, DMD-AR-2023-001373; DOI: https://doi.org/10.1124/dmd.123.001373
You have access
Metabolism and excretion of therapeutic peptides: current industry practices, perspectives, and recommendations
Minxia Michelle He, Sean Xiaochun Zhu, Joe R Cannon, Jesper Kammersgaard Christensen, Ruchia Duggal, Mithat Gunduz, Constanze Hilgendorf, Adam Hughes, Ivy Kekessie, Maximilian Kullmann, Dennis Leung, Carsten Terjung, Kai Wang and Frank Wesche

Drug Metabolism and Disposition August 17, 2023, DMD-AR-2023-001437; DOI: https://doi.org/10.1124/dmd.123.001437

Main menu

User menu

Search

Latest Articles

Pages

Navigate

More Information

ASPET's Other Journals