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In Vitro Evaluation of the Reductase Activities of Human AKR1C3 Allelic Variants
Shiori Takano, Tatsuki Fukami, Hiroyuki Ichida, Kohei Suzuki, Masataka Nakano and Miki Nakajima

Drug Metabolism and Disposition September 2023, 51 (9) 1188-1195; DOI: https://doi.org/10.1124/dmd.123.001264
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Adipocyte-Derived PXR Signaling Is Dispensable for Diet-Induced Obesity and Metabolic Disorders in Mice
Fang Wang, Jingwei Liu, Rebecca Hernandez, Se-Hyung Park, Ying-Jing Lai, Shuxia Wang, Bruce Blumberg and Changcheng Zhou

Drug Metabolism and Disposition September 2023, 51 (9) 1207-1215; DOI: https://doi.org/10.1124/dmd.123.001311
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In Vitro and In Vivo Models for Drug Transport Across the Blood-Testis Barrier
Raymond K. Hau, Stephen H. Wright and Nathan J. Cherrington

Drug Metabolism and Disposition September 2023, 51 (9) 1157-1168; DOI: https://doi.org/10.1124/dmd.123.001288
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Progress in the Quantitative Assessment of Transporter-Mediated Drug–Drug Interactions Using Endogenous Substrates in Clinical Studies
Tatsuki Mochizuki and Hiroyuki Kusuhara

Drug Metabolism and Disposition September 2023, 51 (9) 1105-1113; DOI: https://doi.org/10.1124/dmd.123.001285
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Exploring the boundaries for in vitro-in vivo extrapolation: Use of isolated hepatocytes in co-culture and impact of albumin binding properties in the prediction of clearance of various drug types
Laura Francis, Kayode Ogungbenro, Tom De Bruyn, J Brian Houston and David Hallifax

Drug Metabolism and Disposition August 14, 2023, DMD-AR-2023-001309; DOI: https://doi.org/10.1124/dmd.123.001309
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Central mechanisms of acetaminophen hepatotoxicity: mitochondrial dysfunction by protein adducts and oxidant stress
Hartmut Jaeschke and Anup Ramachandran

Drug Metabolism and Disposition August 11, 2023, DMD-MR-2023-001279; DOI: https://doi.org/10.1124/dmd.123.001279
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Goldenseal-mediated inhibition of intestinal uptake transporters decreases metformin systemic exposure in mice
Victoria O Oyanna, Kenisha Y Garcia-Torres, Baron J Bechtold, Katherine D Lynch, M Ridge Call, Miklós Horváth, Preston K Manwill, Tyler N Graf, Nadja B. Cech, Nicholas H. Oberlies, Mary F. Paine and John D. Clarke

Drug Metabolism and Disposition August 10, 2023, DMD-AR-2023-001360; DOI: https://doi.org/10.1124/dmd.123.001360
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Commentary Kirchhoff's Laws and Hepatic Clearance, Well-Stirred Model - Is There Common Ground?
Malcolm Rowland, Michael Weiss and K. Sandy Pang

Drug Metabolism and Disposition August 10, 2023, DMD-COM-2023-001300; DOI: https://doi.org/10.1124/dmd.123.001300
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The Utility of Mixed-Effects Models in the Evaluation of Complex Genomic Traits In Vitro
Nathan Alade, Abhinav Nath, Nina Isoherranen and Kenneth E. Thummel

Drug Metabolism and Disposition August 10, 2023, DMD-AR-2023-001260; DOI: https://doi.org/10.1124/dmd.123.001260
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CYP2D6 activity is correlated with changes in plasma concentrations of taurocholic acid during pregnancy and postpartum in CYP2D6 extensive metabolizers
Lindsay C Czuba, Karan Malhotra, Luke Enthoven, Emily E Fay, Sue L Moreni, Jennie Mao, Yuanyuan Shi, Weize Huang, Rheem A Totah, Nina Isoherranen and Mary F. Hebert

Drug Metabolism and Disposition August 7, 2023, DMD-AR-2023-001358; DOI: https://doi.org/10.1124/dmd.123.001358

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