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Proteomic and Bioinformatics Analysis of Membrane Lipid Domains after Brij 98 Solubilization of Uninduced and Phenobarbital-Induced Rat Liver Microsomes: Defining the Membrane Localization of the P450 Enzyme System
James R. Reed, Jessie J. Guidry and Wayne L. Backes

Drug Metabolism and Disposition April 2022, 50 (4) 374-385; DOI: https://doi.org/10.1124/dmd.121.000752
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Reevaluate In Vitro CYP3A Index Reactions of Benzodiazepines and Steroids between Humans and Dogs
Qingliang Wu, Yiting Hu, CuiTong Wang, Wei Wei, Lanlan Gui, Wu-shuang Zeng, Changxiao Liu, Wei Jia, Jia Miao and Ke Lan

Drug Metabolism and Disposition March 29, 2022, DMD-AR-2022-000864; DOI: https://doi.org/10.1124/dmd.122.000864
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Is The Protein-Mediated Uptake Of Drugs By OATPs A Real Phenomenon Or An Artifact?
Mengyue Yin, Flavia Storelli and Jashvant D. Unadkat

Drug Metabolism and Disposition March 29, 2022, DMD-AR-2022-000849; DOI: https://doi.org/10.1124/dmd.122.000849
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Predicting impact of food and feeding time on oral absorption of drugs with a novel rat continuous intestinal absorption model
Casey Radice, Ken Korzekwa and Swati Nagar

Drug Metabolism and Disposition March 26, 2022, DMD-AR-2022-000831; DOI: https://doi.org/10.1124/dmd.122.000831
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Label-Free but Still Constrained: Assessment of Global Proteomic Strategies for the Quantification of Hepatic Enzymes and Transporters
Jill Barber, Zubida M. Al-Majdoub, Narciso Couto, Areti-Maria Vasilogianni, Annika Tillmann, Sarah Alrubia, Amin Rostami-Hodjegan and Brahim Achour

Drug Metabolism and Disposition March 20, 2022, DMD-AR-2021-000780; DOI: https://doi.org/10.1124/dmd.121.000780
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Localization of Xenobiotic Transporters Expressed at the Human Blood-Testis Barrier
Raymond K. Hau, Robert R Klein, Stephen H. Wright and Nathan J Cherrington

Drug Metabolism and Disposition March 20, 2022, DMD-AR-2021-000748; DOI: https://doi.org/10.1124/dmd.121.000748
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A Cross Company Perspective on the Assessment of Therapeutic Protein Biotransformation
Markus Walles, Michael J Berna, Wenying Jian, Simon Hauri, Shawna Hengel, Lloyd King, John C Tran, Cong Wei, Keyang Xu and Xiaochun Zhu

Drug Metabolism and Disposition March 19, 2022, DMD-MR-2021-000462; DOI: https://doi.org/10.1124/dmd.121.000462
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Methionine sulfoxide reductase A in human and mouse tissues is responsible for sulindac activation, making a larger contribution than the gut microbiota
Keiya Hirosawa, Tatsuki Fukami, Mai Nagaoka, Masataka Nakano and Miki Nakajima

Drug Metabolism and Disposition March 12, 2022, DMD-AR-2022-000828; DOI: https://doi.org/10.1124/dmd.122.000828
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Cynomolgus Monkey as an Emerging Animal Model to Study Drug Transporters: In Vitro, In Vivo, In Vitro-to-In Vivo Translation
Hong Shen, Zheng Yang and A. David Rodrigues

Drug Metabolism and Disposition March 2022, 50 (3) 299-319; DOI: https://doi.org/10.1124/dmd.121.000695
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Transplacental Pharmacokinetic Model of Digoxin Based on Ex Vivo Human Placental Perfusion Study
Ken Kurosawa, Saki Noguchi, Tomohiro Nishimura, Masatoshi Tomi and Koji Chiba

Drug Metabolism and Disposition March 2022, 50 (3) 287-298; DOI: https://doi.org/10.1124/dmd.121.000648

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