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Characterization of a Novel CYP1A2 Knockout Rat Model Constructed by CRISPR/Cas9
Dongyi Sun, Jian Lu, Yuanjin Zhang, Jie Liu, Zongjun Liu, Bingyi Yao, Yuanqing Guo and Xin Wang

Drug Metabolism and Disposition August 2021, 49 (8) 638-647; DOI: https://doi.org/10.1124/dmd.121.000403
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Feature, Function, and Information of Drug Transporter Related Databases
Jiayi Yin, Fengcheng Li, Zhaorong Li, Lushan Yu, Feng Zhu and Su Zeng

Drug Metabolism and Disposition August 23, 2021, DMD-MR-2021-000419; DOI: https://doi.org/10.1124/dmd.121.000419
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Investigation into MAO B–Mediated Formation of CC112273, a Major Circulating Metabolite of Ozanimod, in Humans and Preclinical Species: Stereospecific Oxidative Deamination of (S)-Enantiomer of Indaneamine (RP101075) by MAO B
April Bai, Veerabahu Shanmugasundaram, Julie V. Selkirk, Sekhar Surapaneni and Deepak Dalvie

Drug Metabolism and Disposition August 2021, 49 (8) 601-609; DOI: https://doi.org/10.1124/dmd.121.000447
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Pharmacokinetics, Disposition, and Biotransformation of [¹⁴C]Omecamtiv Mecarbil in Healthy Male Subjects after a Single Intravenous or Oral Dose
Ashit Trivedi, Jan Wahlstrom, Mia Mackowski, Sandeep Dutta and Edward Lee

Drug Metabolism and Disposition August 2021, 49 (8) 619-628; DOI: https://doi.org/10.1124/dmd.121.000444
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Proteomic Quantification of Changes in Abundance of Drug-Metabolizing Enzymes and Drug Transporters in Human Liver Cirrhosis: Different Methods, Similar Outcomes
Eman El-Khateeb, Zubida M. Al-Majdoub, Amin Rostami-Hodjegan, Jill Barber and Brahim Achour

Drug Metabolism and Disposition August 2021, 49 (8) 610-618; DOI: https://doi.org/10.1124/dmd.121.000484
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BCRP/ABCG2 Transporter Regulates Accumulation of Cadmium in Kidney Cells: Role of the Q141K Variant in Modulating Nephrotoxicity
Xia Wen, Danielle Kozlosky, Ranran Zhang, Cathleen Doherty, Brian Buckley, Emily Barrett and Lauren M. Aleksunes

Drug Metabolism and Disposition August 2021, 49 (8) 629-637; DOI: https://doi.org/10.1124/dmd.121.000446
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Augmented clearance of nivolumab is associated with renal functions in chronic renal disease model rats
Kazuaki Taguchi, Yukitaka Hayashi, Mayu Ohuchi, Hotaka Yamada, Shigehiro Yagishita, Yuki Enoki, Kazuaki Matsumoto and Akinobu Hamada

Drug Metabolism and Disposition August 4, 2021, DMD-AR-2021-000520; DOI: https://doi.org/10.1124/dmd.121.000520
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Alterations of cytochrome P450-mediated drug metabolism during liver repair and regeneration after acetaminophen-induced liver injury in mice
Yifan Bao, Mi Phan, Junjie Zhu, Xiaochao Ma, Jose E. Manautou and Xiao-bo Zhong

Drug Metabolism and Disposition August 4, 2021, DMD-AR-2021-000459; DOI: https://doi.org/10.1124/dmd.121.000459
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Comparative Proteomics Analysis of the Postmitochondrial Supernatant Fraction of Human Lens-Free Whole Eye and Liver
Ankit Balhara, Abdul Basit, Upendra A. Argikar, Jennifer L. Dumouchel, Saranjit Singh and Bhagwat Prasad

Drug Metabolism and Disposition July 2021, 49 (7) 592-600; DOI: https://doi.org/10.1124/dmd.120.000297
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A New Intestinal Model for Analysis of Drug Absorption and Interactions Considering Physiological Translocation of Contents
Satoshi Asano, Aoi Yoshitomo, Shizuka Hozuki, Hiromi Sato, Yasuhiro Kazuki and Akihiro Hisaka

Drug Metabolism and Disposition July 2021, 49 (7) 581-591; DOI: https://doi.org/10.1124/dmd.121.000361

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