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Research ArticleArticle

Regulation of miRNA Expression by Rifampin in Human Hepatocytes

Anuradha Ramamoorthy, Yunlong Liu, Santosh Philips, Zeruesenay Desta, Hai Lin, Chirayu Goswami, Andrea Gaedigk, Lang Li, David A Flockhart and Todd C Skaar
Drug Metabolism and Disposition August 9, 2013, dmd.113.052886; DOI: https://doi.org/10.1124/dmd.113.052886
Anuradha Ramamoorthy
1 Indiana University;
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Yunlong Liu
1 Indiana University;
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Santosh Philips
1 Indiana University;
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Zeruesenay Desta
1 Indiana University;
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Hai Lin
1 Indiana University;
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Chirayu Goswami
1 Indiana University;
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Andrea Gaedigk
2 Children's Mercy Hospital
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Lang Li
1 Indiana University;
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David A Flockhart
1 Indiana University;
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Todd C Skaar
1 Indiana University;
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  • For correspondence: tskaar@iupui.edu

Supplemental Data

Files in this Data Supplement:

  • Supplemental Table 1 -

    Effect of rifampin on CYP mRNA expression levels in hepatocytes

  • Supplemental Table 2 -

    Correlations (r-values) of rifampin-induced changes in the mRNA expression among all CYP genes

  • Supplemental Table 3 -

    miRNAs regulated by rifampin in hepatocytes1

  • Supplemental Table 4 -

    Correlations of miRNA and predicted CYP mRNA expression

  • Supplemental Figure 1 -

    Principal components analysis of rifampin-regulated miRNAs in human hepatocytes

  View article

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