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Research ArticleShort Communication

Evaluation of 23 Lots of Commercially Available Cryopreserved Hepatocytes for Induction Assays of Human Cytochromes P450

Kanako Yajima, Yasuhiro Uno, Norie Murayama, Shotaro Uehara, Makiko Shimizu, Chika Nakamura, Kazuhide Iwasaki, Masahiro Utoh and Hiroshi Yamazaki
Drug Metabolism and Disposition February 19, 2014, dmd.113.056804; DOI: https://doi.org/10.1124/dmd.113.056804
Kanako Yajima
1 Shin Nippon Biomedical Laboratories;
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Yasuhiro Uno
1 Shin Nippon Biomedical Laboratories;
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Norie Murayama
2 Showa Pharmaceutical University
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Shotaro Uehara
1 Shin Nippon Biomedical Laboratories;
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Makiko Shimizu
2 Showa Pharmaceutical University
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Chika Nakamura
1 Shin Nippon Biomedical Laboratories;
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Kazuhide Iwasaki
1 Shin Nippon Biomedical Laboratories;
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Masahiro Utoh
1 Shin Nippon Biomedical Laboratories;
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Hiroshi Yamazaki
2 Showa Pharmaceutical University
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  • For correspondence: hyamazak@ac.shoyaku.ac.jp

Data Supplement

Files in this Data Supplement:

  • Data Supplement -

    Supplemental Table S1 - Clinical characteristics of hepatocyte donors used in this study

    Supplemental Figure S1 - Induction of human CYP2C8, CYP2C9, CYP2C19, and CYP3A4 mRNA in eight lots of cryopreserved hepatocytes and HepaRG cells by rifampicin and phenobarbital

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