Investigational Small-molecule Drug Selectively Suppresses Constitutive CYP2B6 Activity at the Gene Transcription Level: PBPK-based Assessment of Clinical Drug Interaction Risk

Data Supplement

Files in this Data Supplement:

• Data Supplement -

  Supplemental Figure 1 - Structure of LY2090314...

  Supplemental Table 1 - Primary human hepatocyte donor information

  Supplemental Table 2 - Summary of LY2090314 drug-dependent model parameters

  Supplemental Table 3 - Summary of bupropion and hydroxybuproprion drug-dependent model parameters

  Supplemental References