Skip to main content
Advertisement

Main menu

  • Home
  • Articles
    • Current Issue
    • Fast Forward
    • Latest Articles
    • Archive
  • Information
    • Instructions to Authors
    • Submit a Manuscript
    • FAQs
    • For Subscribers
    • Terms & Conditions of Use
    • Permissions
  • Editorial Board
  • Alerts
    • Alerts
    • RSS Feeds
  • Virtual Issues
  • Feedback
  • Other Publications
    • Drug Metabolism and Disposition
    • Journal of Pharmacology and Experimental Therapeutics
    • Molecular Pharmacology
    • Pharmacological Reviews
    • Pharmacology Research & Perspectives
    • ASPET

User menu

  • My alerts
  • Log in
  • My Cart

Search

  • Advanced search
Drug Metabolism & Disposition
  • Other Publications
    • Drug Metabolism and Disposition
    • Journal of Pharmacology and Experimental Therapeutics
    • Molecular Pharmacology
    • Pharmacological Reviews
    • Pharmacology Research & Perspectives
    • ASPET
  • My alerts
  • Log in
  • My Cart
Drug Metabolism & Disposition

Advanced Search

  • Home
  • Articles
    • Current Issue
    • Fast Forward
    • Latest Articles
    • Archive
  • Information
    • Instructions to Authors
    • Submit a Manuscript
    • FAQs
    • For Subscribers
    • Terms & Conditions of Use
    • Permissions
  • Editorial Board
  • Alerts
    • Alerts
    • RSS Feeds
  • Virtual Issues
  • Feedback
  • Visit dmd on Facebook
  • Follow dmd on Twitter
  • Follow ASPET on LinkedIn
Research ArticleArticle

The Need for BCRP Substrate and Inhibition Evaluation in Drug Discovery and Development: Why, When and How?

Agnes Poirier, Renee Portmann, Anne-Christine Cascais, Urs Bader, Isabelle Walter, Mohammed Ullah and Christoph Funk
Drug Metabolism and Disposition July 2, 2014, dmd.114.058248; DOI: https://doi.org/10.1124/dmd.114.058248
Agnes Poirier
1 F.Hoffmann-La Roche Ldt.;
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Renee Portmann
1 F.Hoffmann-La Roche Ldt.;
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Anne-Christine Cascais
1 F.Hoffmann-La Roche Ldt.;
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Urs Bader
1 F.Hoffmann-La Roche Ldt.;
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Isabelle Walter
1 F.Hoffmann-La Roche Ldt.;
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Mohammed Ullah
1 F.Hoffmann-La Roche Ldt.;
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Christoph Funk
2 F. Hoffmann-La Roche Ltd.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • For correspondence: christoph.funk@roche.com

Data Supplement

Files in this Data Supplement:

  • Supplemental Data -

    Supplemental Table 1 - MDR1 substrate in vitro results of drugs tested in L-MDR1 cells at 1 mu-M

    Supplemental Table 2 - Clinical DDI studies...

    References

  View article

  • Home
  • Alerts
Facebook   Twitter   LinkedIn   RSS

Navigate

  • Current Issue
  • Fast Forward by date
  • Fast Forward by section
  • Latest Articles
  • Archive
  • Search for Articles
  • Feedback
  • ASPET

More Information

  • About DMD
  • Editorial Board
  • Instructions to Authors
  • Submit a Manuscript
  • Customized Alerts
  • RSS Feeds
  • Subscriptions
  • Permissions
  • Terms & Conditions of Use

ASPET's Other Journals

  • Journal of Pharmacology and Experimental Therapeutics
  • Molecular Pharmacology
  • Pharmacological Reviews
  • Pharmacology Research & Perspectives
ISSN 1521-009X (Online)

Copyright © 2021 by the American Society for Pharmacology and Experimental Therapeutics