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Research ArticleArticle

Cynomolgus Monkey as a Surrogate for Human Aldehyde Oxidase Metabolism of the EGFR Inhibitor BIBX1382

J. Matthew Hutzler, Matthew A. Cerny, Young-Sun Yang, Constance Asher, Diane Wong, Kosea Frederick and Kyle Gilpin
Drug Metabolism and Disposition July 17, 2014, dmd.114.059030; DOI: https://doi.org/10.1124/dmd.114.059030

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    Supplemental Figure 1 - Inhibition of M1 (BIBU1476) and M2 formation in cynomolgus monkey liver S9 fraction...

    Supplemental Figure 2 - Inhibition of BIBU1476 (M1) formation in cynomolgus monkey lung S9 fraction...

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