Investigation of the Impact of Substrate Selection on In Vitro Organic Anion Transporting Polypeptide 1B1 Inhibition Profiles for the Prediction of Drug-Drug Interactions

Data Supplement

Files in this Data Supplement:

• Supplemental Tables -

  Supplemental Table 1 - Kinetic parameters of inhibitors used for the calculation of R-values

  Supplemental Table 2 - IC50 values of CsA, rifampin, and gemfibrozil for OATP1B1-mediated uptake of clinically-used OATP1B1 substrate drugs

  Supplemental Table 3 - Reported IC50 or Ki values of CsA, rifampin, and gemfibrozil for OATP1B1-mediated uptake of prototypical substrates or clinically-used OATP1B1 substrate drugs