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Research ArticleMinireview

Breast Cancer Resistance Protein (ABCG2) in Clinical Pharmacokinetics and Drug Interactions: Practical Recommendations for Clinical Victim and Perpetrator Drug-Drug Interaction Study Design

Caroline A Lee, Meeghan A O'Connor, Tasha K Ritchie, Aleksandra Galetin, Jack A Cook, Isabelle Ragueneau-Majlessi, Harma Ellens, Bo Feng, Mitchell E Taub, Mary F Paine, Joseph W Polli, Joseph A Ware and Maciej J Zamek-Gliszczynski
Drug Metabolism and Disposition January 13, 2015, dmd.114.062174; DOI: https://doi.org/10.1124/dmd.114.062174
Caroline A Lee
1 Ardea Bioscience Inc.;
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Meeghan A O'Connor
2 Boehringer-Ingelheim;
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Tasha K Ritchie
3 University of Washington;
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Aleksandra Galetin
4 Manchester Pharmacy School;
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Jack A Cook
5 Pfizer;
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Isabelle Ragueneau-Majlessi
3 University of Washington;
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Harma Ellens
6 GlaxoSmithKline;
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Bo Feng
5 Pfizer;
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Mitchell E Taub
2 Boehringer-Ingelheim;
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Mary F Paine
7 Washington State University;
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Joseph W Polli
6 GlaxoSmithKline;
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Joseph A Ware
8 Genentech
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Maciej J Zamek-Gliszczynski
6 GlaxoSmithKline;
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  • For correspondence: mzg@unc.edu

Data Supplement

Files in this Data Supplement:

  • Supplemental Table -

    Supplemental Table 1 - Clinically usable compounds and in vitro to in vivo translation inhibition calculations (I1/IC50 and I2/IC50)

    References

  View article

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