In Vitro-In Vivo Extrapolation Scaling Factors for Intestinal P-glycoprotein and Breast Cancer Resistance Protein: Part I: A Cross- Laboratory Comparison of Transporter Protein Abundances and Relative Expression Factors in Human Intestine and Caco-2 Cells

Data Supplement

Files in this Data Supplement:

• Supplemental Data -

  Supplemental Table 1 - Intestinal donor demographic information

  Supplemental Table 2 - Analytical quality control validation for Na/K-ATPase by Bertin Pharma<P< Supplemental Table 3 - Analytical quality control validation for P-gp by Bertin Pharma

  Supplemental Table 4 - Analytical quality control validation for BCRP by Bertin Pharma

  Supplemental Figure 1 - Na/K-ATPase amino acid sequence highlighting the BPh selected peptide in bold and underlined text and UoM peptide in bold text

  Supplemental Figure 2 - P-gp amino acid sequence highlighting the BPh selected peptide in bold and underlined text and UoM peptide in bold text

  Supplemental Figure 3 - BCRP amino acid sequence highlighting the BPh selected peptide in bold and underlined text and UoM peptide in bold text