In Vitro-In Vivo Extrapolation Scaling Factors for Intestinal P-glycoprotein and Breast Cancer Resistance Protein: Part II. The Impact of Cross-Laboratory Variations of Intestinal Transporter Relative Expression Factors on Predicted Drug Disposition

Data Supplement

Files in this Data Supplement:

• Supplemental Data -

  Supplemental Table 1 - Publications reporting P-gp (MDR1) and BCRP mRNA and protein expression in human jejunum obtained from literature analysis

  TECHNICAL NOTE: RATIONALE FOR BUILDING TC

  Supplemental Figure 1 - Assessing the impact of small intestinal transit time (SITT) (0.5, 3.5, 6.5 and 9.5 hours) on the regional fa in all intestinal compartments

  REFERENCES