Data Supplement
Files in this Data Supplement:
- Supplemental Data -
NMR characterization of synthesized compound AZ13478123 Methods
Supplemental Figure 1 - 600 MHz 1H spectra of AZ13478123 (top) and AZD1979 ( bottom) in CD3OD at 25 deg
Supplemental Figure 2 - 150 MHz 13C spectra of AZ13478123 (top) and AZD1979 (bottom) in CD3OD at 25 deg
Supplemental Figure 3 - 1H -13C HMBC long-range correlation from CH2(5,7) to CH2(8) of AZ13478123
Supplemental Table 1 - NMR assignments for 3-(4-{3,3-bis(hydroxymethyl)azetidin-1- ylmethyl}phenoxy)azetidin-1-yl5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-ylmethanone (AZ13478123) and AZD1979
Supplemental Figure 4 - Comparison of extracted ion chromatograms of AZD1979 and M1 (mass tolerance 10 ppm) in samples without (A and C) and with (B and D) the spiking of the synthesized diol, AZ13478123