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Research ArticleArticle

Determination of Unbound Partition Coefficient (Kpuu) and in Vitro-in Vivo Extrapolation for SLC13A Transporter-Mediated Uptake

Li Di, Keith Riccardi, Zhenhong Li, Janice A. Brown, Matthew F. Gorgoglione, Mark Niosi, James Gosset, Kim Huard and Derek M. Erion
Drug Metabolism and Disposition July 14, 2016, dmd.116.071837; DOI: https://doi.org/10.1124/dmd.116.071837
Li Di
Pfizer Inc.
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  • For correspondence: li.di@pfizer.com
Keith Riccardi
Pfizer Inc.
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Zhenhong Li
Pfizer Inc.
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Janice A. Brown
Pfizer Inc.
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Matthew F. Gorgoglione
Pfizer Inc.
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Mark Niosi
Pfizer Inc.
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James Gosset
Pfizer Inc.
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Kim Huard
Pfizer Inc.
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Derek M. Erion
Pfizer Inc.
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Data Supplement

Files in this Data Supplement:

  • Supplemental Data -

    Supplemental Figure 1 - Diagnosis Plots of Model Fitting

    Supplemental Table 1 - Model Parameters

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