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Research ArticleArticle

Verification of a Maternal-Fetal Physiologically Based Pharmacokinetic Model for Passive Placental Permeability Drugs

Zufei Zhang and Jashvant D. Unadkat
Drug Metabolism and Disposition January 3, 2017, dmd.116.073957; DOI: https://doi.org/10.1124/dmd.116.073957

Data Supplement

Files in this Data Supplement:

  • Supplemental Data -

    Supplemental Figure 1 - shows the structure of the MATLAB PBPK model for the non-pregnant population

    Supplemental Figure 2 - Impact of varying the unbound transplacental passive diffusion clearance (CLPD,u)of midazolam, theophylline, and zidovudine on their maternal plasma...

    Supplemental Table 1 - Sensitivity analysis of midazolam transplacental passive diffusion clearance (CLPD,MDZ)

    Supplementary Methods

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