Elucidation of the impact of P-glycoprotein and Breast Cancer Resistance Protein on the brain distribution of catechol-O-methyltransferase inhibitors

Data Supplement

• Supplemental Tables -

  Supplemental Table 1 - Chromatographic conditions and validation parameters of HPLC-DAD techniques applied for the quantification of reference and test compounds in samples from in vitro and in vivo assays
  

  Supplemental Table 2 - Stability (values in percentage) of COMT inhibitors in HBSS with 10mM HEPES pH 7.4 under cellular assay conditions (37º C for 120 min)